Evidence map›Paper›PMID 28167544›Full record

ArticleAntimicrobial agents and chemotherapy2017

Nanoliposomal Buparvaquone Immunomodulates Leishmania infantum-Infected Macrophages and Is Highly Effective in a Murine Model.

Thais Alves da Costa-Silva, Andrés Jimenez Galisteo, José Angelo Lauletta Lindoso, Leandro R S Barbosa, Andre Gustavo Tempone

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Antimicrobial agents and chemotherapy · 2025
    Article
  3. Article
  4. Article
  5. Modulation of CXCL10 activity as a therapeutic target of ocular toxoplasmosis in diabetic mice.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Metabolic Pathways ofPharmaceutics · 2022
    Review
  10. Antimicrobial agents and chemotherapy · 2021
    Article
  11. Article
  12. Review
  13. Article
  14. Nanoparticulate drug delivery systems for the treatment of neglected tropical protozoan diseases.The journal of venomous animals and toxins including tropical diseases · 2019
    Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Thais Alves da Costa-SilvaCentre for Parasitology and Mycology, Instituto Adolfo Lutz, São Paulo, Brazil.
Andrés Jimenez GalisteoInstituto de Medicina Tropical, São Paulo, Brazil.
José Angelo Lauletta LindosoInstituto de Medicina Tropical, São Paulo, Brazil.
Leandro R S BarbosaInstituto de Física da Universidade de São Paulo, São Paulo, Brazil.
Andre Gustavo TemponeCentre for Parasitology and Mycology, Instituto Adolfo Lutz, São Paulo, Brazil atempone@usp.br.
Instituto Adolfo Lutz · BRInstituto de Medicina Avançada · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visceral leishmaniasis is a fatal parasitic neglected disease affecting 1.5 million people worldwide. Based on a drug repositioning approach, the aim of this work was to investigate the

Indexed as

Administration, CutaneousAnimalsAntiprotozoal AgentsBone MarrowChemokine CCL2CricetinaeDisease Models, AnimalDrug CompoundingImmunologic FactorsInterleukin-10Interleukin-6Leishmania infantumLeishmaniasis, VisceralLiposomesLiverMacrophagesAntiprotozoal AgentsbuparvaquoneCcl2 protein, mouseChemokine CCL2IL10 protein, mouseImmunologic FactorsInterleukin-10Interleukin-6interleukin-6, mouseLiposomesNaphthoquinonesTumor Necrosis Factor-alphadrug deliveryLeishmanialiposomestherapy

Identifiers

PMID28167544
PMCPMC5365673
OpenAlexW2587600437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.