Evidence map›Paper›PMID 28167534›Full record

ArticleThe Journal of biological chemistry2017

Detection of lipid-induced structural changes of the Marburg virus matrix protein VP40 using hydrogen/deuterium exchange-mass spectrometry.

Kaveesha J Wijesinghe, Sarah Urata, Nisha Bhattarai, Edgar E Kooijman, Bernard S Gerstman, Prem P Chapagain, Sheng Li, Robert V Stahelin

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Physico-Chemical Mechanisms of the Functioning of Membrane-Active Proteins of Enveloped Viruses.Biochemistry (Moscow) Supplement. Series A, Membrane and cell biology · 2022
    Article
  5. Article
  6. Review
  7. Compound FC-10696 Inhibits Egress of Marburg Virus.Antimicrobial agents and chemotherapy · 2021
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Kaveesha J WijesingheFrom the Department of Chemistry and Biochemistry, The Eck Institute for Global Health and The Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, Indiana 46556.
Sarah Uratathe Department of Medicine, University of California, San Diego, La Jolla, California 92093-0652.
Nisha Bhattaraithe Departments of Physics and.
Edgar E Kooijmanthe Department of Biological Sciences, Kent State University, Kent, Ohio 44242, and.
Bernard S Gerstmanthe Departments of Physics and.
Prem P Chapagainthe Departments of Physics and.
Sheng Lithe Department of Medicine, University of California, San Diego, La Jolla, California 92093-0652, s4li@ucsd.edu.
Robert V StahelinFrom the Department of Chemistry and Biochemistry, The Eck Institute for Global Health and The Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, Indiana 46556, rstaheli@iu.edu.
Florida International University · USUniversity of California, San Diego · USIndiana University School of MedicineKent State University · USUniversity of Notre Dame · US

Funding

Structure based design of antibodies and vaccinesU19AI117905 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SCHIEF, WILLIAM R. · 2015 to 2019
$12.0M
ACTION OF LIPOLYTIC ENZYMESR01GM020501 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DENNIS, EDWARD A · 1985 to 2020
$7.3M
Mechanism of receptor-mediated entry and infection by filovirusesR01AI101436 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CHANDRAN, KARTIK · 2012 to 2016
$4.0M
Chemistry-Biochemistry-Biology Training Program at Notre DameT32GM075762 · NIGMS · UNIVERSITY OF NOTRE DAME · PI CHANG, MAYLAND F, MOBASHERY, SHAHRIAR · 2007 to 2021
$3.7M
LIPID-PROTEIN INTERACTIONS IN VIRAL ASSEMBLY AND VIRUS LIKE PARTICLE FORMATIONR01AI081077 · NIAID · PURDUE UNIVERSITY · PI STAHELIN, ROBERT VIRGIL · 2009 to 2019
$3.5M
NIAID NIH HHS R01 AI081077NIAID NIH HHS R01 AI101436NIAID NIH HHS U19 AI117905NIGMS NIH HHS R01 GM020501NIGMS NIH HHS T32 GM075762
6 · The paper itself

Abstract

Marburg virus (MARV) is a lipid-enveloped virus from the

Indexed as

Models, ChemicalProtein MultimerizationDeuterium Exchange MeasurementMarburgvirusMass SpectrometryPhosphatidylcholinesPhosphatidylserinesProtein Structure, QuaternaryViral Matrix Proteins1-palmitoyl-2-oleoylglycero-3-phosphoserine1-palmitoyl-2-oleoylphosphatidylcholinePhosphatidylcholinesPhosphatidylserinesViral Matrix ProteinsVP40 protein, virusEbola virusFilovirushydrogen-deuterium exchangeMarburg Virusmass spectrometry (MS)oligomerizationphosphatidylserineplasma membraneviral buddingVP40

Identifiers

PMID28167534
PMCPMC5391744
OpenAlexW2586779340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.