Evidence map›Paper›PMID 28167530›Full record

ArticleThe Journal of biological chemistry2017

Mutational Analysis of the QRRQ Motif in the Yeast Hig1 Type 2 Protein Rcf1 Reveals a Regulatory Role for the Cytochrome

Joshua Garlich, Valentina Strecker, Ilka Wittig, Rosemary A Stuart

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Structure and function of theProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  13. Article
  14. Article
  15. Cryo-EM structure of the yeast respiratory supercomplex.Nature structural & molecular biology · 2019
    Article
  16. Rcf1 Modulates CytochromeFrontiers in physiology · 2019
    Article
  17. Article
  18. Article
  19. Respiratory chain supercomplexes: Structures, function and biogenesis.Seminars in cell & developmental biology · 2018
    Review
  20. Mitochondrial cytochrome c oxidase biogenesis: Recent developments.Seminars in cell & developmental biology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Joshua GarlichFrom the Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53233 and.
Valentina StreckerFunctional Proteomics, SFB 815 Core Unit, Goethe-Universität, 60590 Frankfurt am Main, Germany.
Ilka WittigFunctional Proteomics, SFB 815 Core Unit, Goethe-Universität, 60590 Frankfurt am Main, Germany.
Rosemary A StuartFrom the Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53233 and rosemary.stuart@marquette.edu.
Goethe University Frankfurt · DEMarquette University · US

Funding

Mitochondrial OXPHOS regulation and the Rcf1/Hig1 protein family - a functional link between the ADP/ATP carrier and cytochrome c oxidase enzymesR15GM117551 · NIGMS · MARQUETTE UNIVERSITY · PI STUART, ROSEMARY A · 2016 to 2016
$444k
The Hig1 protein family and the cytochrome c oxidase complexR15GM101594 · NIGMS · MARQUETTE UNIVERSITY · PI STUART, ROSEMARY A · 2012 to 2012
$337k
NIGMS NIH HHS R15 GM101594NIGMS NIH HHS R15 GM117551
6 · The paper itself

Abstract

The yeast Rcf1 protein is a member of the conserved family of proteins termed the hypoxia-induced gene (domain) 1 (Hig1 or HIGD1) family. Rcf1 interacts with components of the mitochondrial oxidative phosphorylation system, in particular the cytochrome

Indexed as

DNA Mutational AnalysisAmino Acid MotifsCardiolipinsElectron Transport Complex IIIElectron Transport Complex IVMitochondrial ProteinsMutationSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCardiolipinsElectron Transport Complex IIIElectron Transport Complex IVMitochondrial ProteinsRcf1 protein, S cerevisiaeSaccharomyces cerevisiae Proteinsbioenergeticscardiolipincytochrome c oxidase (complex IV)Hig1mitochondriaRcf1yeast

Identifiers

PMID28167530
PMCPMC5392669
OpenAlexW2587104291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.