ArticleNeuroImage2017
3D functional ultrasound imaging of the cerebral visual system in rodents.
Article in NeuroImage, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 101 citations in OpenAlex.
- Functional ultrasound imaging reveals early pathway-specific reorganization of central visual circuits in a mouse model of Batten disease.Neurobiology of disease · 2026Article
- Functional ultrasound imaging reveals pathway-specific visual system reorganization in youngbioRxiv : the preprint server for biology · 2026Article
- Principles of Doppler ultrasound and emerging blood flow imaging.Ultrasonography (Seoul, Korea) · 2025Article
- Exploring Neural Dynamics in the Auditory Telencephalon of Crows Using Functional Ultrasound Imaging.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Induction of haemodynamic travelling waves by glial-related vasomotion in a rat model of neuroinflammation: implications for functional neuroimaging.EBioMedicine · 2025Article
- Transcranial brain-wide functional ultrasound and ultrasound localization microscopy in mice using multi-array probes.Scientific reports · 2025Article
- Article
- Functional ultrasound and brain connectivity reveal central nervous system compromise in Trembler-J mice model of Charcot-Marie-Tooth disease.Scientific reports · 2024Article
- Ultrasound Flow Imaging Study on Rat Brain with Ultrasound and Light Stimulations.Bioengineering (Basel, Switzerland) · 2024Article
- Waxholm Space atlas of the rat brain: a 3D atlas supporting data analysis and integration.Nature methods · 2023Article
- Mapping Pharmacologically Evoked Neurovascular Activation and Its Suppression in a Rat Model of Tremor Using Functional Ultrasound: A Feasibility Study.Sensors (Basel, Switzerland) · 2023Article
- Microscale acoustic metamaterials as conformal sonotransparent skull prostheses.Research square · 2023Article
- Deconvolution of the Functional Ultrasound Response in the Mouse Visual Pathway Using Block-Term Decomposition.Neuroinformatics · 2023Article
- Functional ultrasound imaging reveals 3D structure of orientation domains in ferret primary visual cortex.NeuroImage · 2023Article
- Functional ultrasound detects frequency-specific acute and delayed S-ketamine effects in the healthy mouse brain.Frontiers in neuroscience · 2023Article
- The Emergence of Functional Ultrasound for Noninvasive Brain-Computer Interface.Research (Washington, D.C.) · 2023Review
- High sensitivity mapping of brain-wide functional networks in awake mice using simultaneous multi-slice fUS imaging.Imaging neuroscience (Cambridge, Mass.) · 2023Article
- A neuroscientist's guide to using murine brain atlases for efficient analysis and transparent reporting.Frontiers in neuroinformatics · 2023Article
- Retinal functional ultrasound imaging (rfUS) for assessing neurovascular alterations: a pilot study on a rat model of dementia.Scientific reports · 2022Article
- High-resolution micro-Doppler imaging during neurosurgical resection of an arteriovenous malformation: illustrative case.Journal of neurosurgery. Case lessons · 2022Article
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
3D functional imaging of the whole brain activity during visual task is a challenging task in rodents due to the complex tri-dimensional shape of involved brain regions and the fine spatial and temporal resolutions required to reveal the visual tract. By coupling functional ultrasound (fUS) imaging with a translational motorized stage and an episodic visual stimulation device, we managed to accurately map and to recover the activity of the visual cortices, the Superior Colliculus (SC) and the Lateral Geniculate Nuclei (LGN) in 3D. Cerebral Blood Volume (CBV) responses during visual stimuli were found to be highly correlated with the visual stimulus time profile in visual cortices (r=0.6), SC (r=0.7) and LGN (r=0.7). These responses were found dependent on flickering frequency and contrast, and optimal stimulus parameters for largest CBV increases were obtained. In particular, increasing the flickering frequency higher than 7Hz revealed a decrease of visual cortices response while the SC response was preserved. Finally, cross-correlation between CBV signals exhibited significant delays (d=0.35s +/-0.1s) between blood volume response in SC and visual cortices in response to our visual stimulus. These results emphasize the interest of fUS imaging as a whole brain neuroimaging modality for brain vision studies in rodent models.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.