Evidence map›Paper›PMID 28167264›Full record

ArticleInternational journal of pharmaceutics2017

Surface-modified particles loaded with CaMKII inhibitor protect cardiac cells against mitochondrial injury.

Amaraporn Wongrakpanich, Angie S Morris, Sean M Geary, Mei-Ling A Joiner, Aliasger K Salem

Open access · greenAbstract read
In one paragraph

Article in International journal of pharmaceutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  6. Review
  7. Sustained Release of Hydrogen Sulfide (HAnnals of biomedical engineering · 2019
    Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Amaraporn WongrakpanichDepartment of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, United States; Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand. Electronic address: amaraporn.won@mahidol.ac.th.
Angie S MorrisDepartment of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, United States.
Sean M GearyDepartment of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, United States.
Mei-Ling A JoinerDepartment of Molecular Physiology & Biophysics, Carver College of Medicine, University of Iowa, Iowa City, IA 52241, United States. Electronic address: mei-ling-joiner@uiowa.edu.
Aliasger K SalemDepartment of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, United States. Electronic address: aliasger-salem@uiowa.edu.
University of Iowa · USMahidol University · TH

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Christopher K Laubenthal · 2000 to 2026
$70.0M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5M
University of Iowa Institutional Training Program in Oral Health ResearchT90DE023520 · NIDCR · UNIVERSITY OF IOWA · PI STEVEN M. LEVY · 2013 to 2026
$5.6M
Regulation of Neuronal Calcium ChannelsR01NS084190 · NINDS · UNIVERSITY OF IOWA · PI LEE, AMY · 2014 to 2018
$2.2M
NCI NIH HHS P30 CA086862NIDCR NIH HHS T90 DE023520NIEHS NIH HHS P30 ES005605NINDS NIH HHS R01 NS084190
6 · The paper itself

Abstract

An excess of calcium (Ca

Indexed as

AnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2Cell DeathCells, CulturedIsoproterenolLactic AcidMembrane Potential, MitochondrialMitochondria, HeartMyocytes, CardiacOrganophosphorus CompoundsPeptidesPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerProtective AgentsRatsReactive Oxygen SpeciesCalcium-Calmodulin-Dependent Protein Kinase Type 2IsoproterenolLactic AcidOrganophosphorus CompoundsPeptidesPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerProtective AgentsReactive Oxygen SpeciesCaMKIIMitochondria targetingPLGA

Identifiers

PMID28167264
PMCPMC5401631
OpenAlexW2583734028

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.