ArticleParasites & vectors2017
Prevalence, genetic identity and vertical transmission of Babesia microti in three naturally infected species of vole, Microtus spp. (Cricetidae).
Article in Parasites & vectors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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42 citing papers in PubMed.
- Molecular identification of cestodes from rodents in the Mazury Lake District region of Poland.Parasitology research · 2026Article
- Prevalence and genetic diversity of Babesia microti in rodents from central and southern Shanxi, China.Parasites & vectors · 2025Article
- A survey for piroplasmids in questing Ixodes fuscipes ticks reveals undescribed Babesia lineages in Uruguay.Parasites & vectors · 2025Article
- Are you ready for the tick season? Spring dynamic of tick diversity and density in urban and suburban areas.Parasites & vectors · 2025Article
- Genetic diversity of Bartonella spp. in rodents and fleas from Poland.Scientific reports · 2025Article
- Small mammals as hosts of vector-borne pathogens in the High Tatra Mountains region in Slovakia, Central Europe.Current research in parasitology & vector-borne diseases · 2025Article
- Development of Multiplex Assays for the Identification of ZoonoticPathogens (Basel, Switzerland) · 2024Article
- Tick-Borne Diseases and Pregnancy: A Narrative Review Evaluating Pregnancy Complications Caused by Tick-Borne Diseases.Tropical medicine and infectious disease · 2024Review
- Pathogens detected in ticks (Ixodes ricinus) feeding on red squirrels (Sciurus vulgaris) from city parks in Warsaw.Experimental & applied acarology · 2024Article
- Host-pathogen associations inferred from bloodmeal analyses ofApplied and environmental microbiology · 2024Article
- Description ofInternational journal for parasitology. Parasites and wildlife · 2024Article
- Prevalence and molecular detection of Babesia microti in rodents in Southeastern Shanxi, China.PloS one · 2024Article
- Detection of a novel Babesia sp. in Amblyomma javanense, an ectoparasite of Sunda pangolins.Parasites & vectors · 2023Article
- Vector-borne parasites in dogs from Ukraine translocated to Poland following Russian invasion in 2022.Parasites & vectors · 2023Article
- Histopathological Analysis of Selected Organs of Rats with Congenital Babesiosis Caused byVeterinary sciences · 2023Article
- Candidatus Neoehrlichia mikurensis and Hepatozoon sp. in voles (Microtus spp.): occurrence and evidence for vertical transmission.Scientific reports · 2023Article
- Repurposing of the Malaria Box for Babesia microti in mice identifies novel active scaffolds against piroplasmosis.Parasites & vectors · 2022Article
- Article
- Babesiosis in Southeastern, Central and Northeastern Europe: An Emerging and Re-Emerging Tick-Borne Disease of Humans and Animals.Microorganisms · 2022Review
- Tick-Borne Pathogens,Pathogens (Basel, Switzerland) · 2022Article
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8 authors.
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Abstract
backgroundVertical transmission is one of the transmission routes for Babesia microti, the causative agent of the zoonotic disease, babesiosis. Congenital Babesia invasions have been recorded in laboratory mice, dogs and humans. The aim of our study was to determine if vertical transmission of B. microti occurs in naturally-infected reservoir hosts of the genus Microtus.
methodsWe sampled 124 common voles, Microtus arvalis; 76 root voles, M. oeconomus and 17 field voles, M. agrestis. In total, 113 embryos were isolated from 20 pregnant females. Another 11 pregnant females were kept in the animal house at the field station in Urwitałt until they had given birth and weaned their pups (n = 62). Blood smears and/or PCR targeting the 550 bp 18S rRNA gene fragment were used for the detection of B. microti. Selected PCR products, including isolates from females/dams and their embryos/pups, were sequenced.
resultsPositive PCR reactions were obtained for 41% (89/217) of the wild-caught voles. The highest prevalence of B. microti was recorded in M. arvalis (56/124; 45.2%), then in M. oeconomus (30/76; 39.5%) and the lowest in M. agrestis (3/17; 17.7%). Babesia microti DNA was detected in 61.4% (27/44) of pregnant females. Vertical transmission was confirmed in 81% (61/75) of the embryos recovered from Babesia-positive wild-caught pregnant females. The DNA of B. microti was detected in the hearts, lungs and livers of embryos from 98% of M. arvalis, 46% of M. oeconomus and 0% of M. agrestis embryos from Babesia-positive females. Of the pups born in captivity, 90% were born to Babesia-positive dams. Babesia microti DNA was detected in 70% (35/50) of M. arvalis and 83% (5/6) of M. oeconomus pups. Congenitally acquired infections had no impact on the survival of pups over a 3-week period post partum. Among 97 B. microti sequences, two genotypes were found. The IRU1 genotype (Jena-like) was dominant in wild-caught voles (49/53; 92%), pregnant females (9/11; 82%) and dams (3/5; 60%). The IRU2 genotype (Munich-like) was dominant among B. microti positive embryos (20/27; 74%) and pups (12/17; 71%).
conclusionA high rate of vertical transmission of the two main rodent genotypes of B. microti was confirmed in two species of naturally infected voles, M. arvalis and M. oeconomus.
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