Evidence map›Paper›PMID 28166784›Full record

Trial reportBMC neurology2017

Randomized controlled trial of a coordinated care intervention to improve risk factor control after stroke or transient ischemic attack in the safety net: Secondary stroke prevention by Uniting Community and Chronic care model teams Early to End Disparities (SUCCEED).

Amytis Towfighi, Eric M Cheng, Monica Ayala-Rivera, Heather McCreath, Nerses Sanossian, Tara Dutta, Bijal Mehta, Robert Bryg, Neal Rao, Shlee Song and 23 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01763203 (Secondary Stroke Prevention by Uniting Community and Chronic Care Model Teams Early to End Disparities), which is not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01763203 nacompletednot on this map

Secondary Stroke Prevention by Uniting Community and Chronic Care Model Teams Early to End Disparities: the SUCCEED Trial

TypeinterventionalSponsorUniversity of California, Los AngelesRan2014 to 2019Enrolled487ConditionsStroke, Secondary Stroke PreventionArmsCare Management+Community Health Worker, Usual Care
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 13 institutions in 1 country.

Amytis TowfighiLos Angeles County Department of Health Services, Los Angeles, California, USA. towfighi@usc.edu.ORCID http://orcid.org/0000-0002-9565-6787
Eric M ChengUniversity of California, Los Angeles (UCLA), Los Angeles, California, USA.
Monica Ayala-RiveraRancho Los Amigos National Rehabilitation Center, Downey, California, USA.
Heather McCreathUniversity of California, Los Angeles (UCLA), Los Angeles, California, USA.
Nerses SanossianUniversity of Southern California, Los Angeles, California, USA.
Tara DuttaRancho Los Amigos National Rehabilitation Center, Downey, California, USA.
Bijal MehtaUniversity of California, Los Angeles (UCLA), Los Angeles, California, USA.
Robert BrygUniversity of California, Los Angeles (UCLA), Los Angeles, California, USA.
Neal RaoUniversity of California, Los Angeles (UCLA), Los Angeles, California, USA.
Shlee SongCedars Sinai Medical Center, Los Angeles, California, USA.
Ali RazmaraRancho Los Amigos National Rehabilitation Center, Downey, California, USA.
Magaly RamirezFielding School of Public Health, Department of Health Policy and Management, University of California, Los Angeles, Los Angeles, California, USA.
Theresa Sivers-TeixeiraUniversity of Southern California, Los Angeles, California, USA.
Jamie TranHarbor-UCLA Medical Center, Torrance, California, USA.
Elizabeth Mojarro-HuangRancho Los Amigos National Rehabilitation Center, Downey, California, USA.
Ana MontoyaRancho Los Amigos National Rehabilitation Center, Downey, California, USA.
Marilyn CorralesLos Angeles County Department of Health Services, Los Angeles, California, USA.
Beatrice MartinezRancho Los Amigos National Rehabilitation Center, Downey, California, USA.
Phyllis WillisWatts Labor Community Action Committee, Watts, California, USA.
Mireya MaciasWorker Education and Resource Center, Los Angeles, California, USA.
Nancy IbrahimEsperanza Community Housing, Los Angeles, California, USA.
Shinyi WuSchool of Social Work, Edward R. Roybal Institute on Aging, and Daniel J. Epstein Department of Industrial and Systems Engineering, University of Southern California, Los Angeles, California, USA.
Jeremy WacksmanDimagi, Inc., Cambridge, Massachusetts, USA.
Hilary HaberDimagi, Inc., Cambridge, Massachusetts, USA.
Adam RichardsUniversity of California, Los Angeles (UCLA), Los Angeles, California, USA.
Frances BarryUniversity of California, Los Angeles (UCLA), Los Angeles, California, USA.
Valerie HillRancho Los Amigos National Rehabilitation Center, Downey, California, USA.
Brian MittmanDepartment of Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California, USA.
William CunninghamUniversity of California, Los Angeles (UCLA), Los Angeles, California, USA.
Honghu LiuUniversity of California, Los Angeles (UCLA), Los Angeles, California, USA.
David A GanzUniversity of California, Los Angeles (UCLA), Los Angeles, California, USA.
Diane FactorWorker Education and Resource Center, Los Angeles, California, USA.
Barbara G VickreyUniversity of California, Los Angeles (UCLA), Los Angeles, California, USA.
University of California, Los Angeles · USUniversity of Southern California · USUCLA Medical Center · USCare Resource · USDimagi (United States) · USKaiser Permanente · USCedars-Sinai Medical Center · USCommunity Living · USLAC+USC Medical Center · USLos Angeles County Department of Health Services · USRancho Los Amigos National Rehabilitation Center · USRAND Corporation · USVA Greater Los Angeles Healthcare System · US

Funding

Secondary Stroke prevention by Uniting Community and Chronic care model teams Early to End Disparities: the SUCCEED TrialU54NS081764 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SEEMAN, TERESA E · 2012 to 2016
$11.3M
Live Well After Stroke: a community-based, life management interventionK99MD010471 · NIMHD · RANCHO RESEARCH INSTITUTE · PI HILL, VALERIE ANN · 2016 to 2017
$268k
NIMHD NIH HHS K99 MD010471NINDS NIH HHS U54 NS081764
6 · The paper itself

Abstract

backgroundRecurrent strokes are preventable through awareness and control of risk factors such as hypertension, and through lifestyle changes such as healthier diets, greater physical activity, and smoking cessation. However, vascular risk factor control is frequently poor among stroke survivors, particularly among socio-economically disadvantaged blacks, Latinos and other people of color. The Chronic Care Model (CCM) is an effective framework for multi-component interventions aimed at improving care processes and outcomes for individuals with chronic disease. In addition, community health workers (CHWs) have played an integral role in reducing health disparities; however, their effectiveness in reducing vascular risk among stroke survivors remains unknown. Our objectives are to develop, test, and assess the economic value of a CCM-based intervention using an Advanced Practice Clinician (APC)-CHW team to improve risk factor control after stroke in an under-resourced, racially/ethnically diverse population. METHODS/

designIn this single-blind randomized controlled trial, 516 adults (≥40 years) with an ischemic stroke, transient ischemic attack or intracerebral hemorrhage within the prior 90 days are being enrolled at five sites within the Los Angeles County safety-net setting and randomized 1:1 to intervention vs usual care. Participants are excluded if they do not speak English, Spanish, Cantonese, Mandarin, or Korean or if they are unable to consent. The intervention includes a minimum of three clinic visits in the healthcare setting, three home visits, and Chronic Disease Self-Management Program group workshops in community venues. The primary outcome is blood pressure (BP) control (systolic BP <130 mmHg) at 1 year. Secondary outcomes include: (1) mean change in systolic BP; (2) control of other vascular risk factors including lipids and hemoglobin A1c, (3) inflammation (C reactive protein [CRP]), (4) medication adherence, (5) lifestyle factors (smoking, diet, and physical activity), (6) estimated relative reduction in risk for recurrent stroke or myocardial infarction (MI), and (7) cost-effectiveness of the intervention versus usual care. DISCUSSION: If this multi-component interdisciplinary intervention is shown to be effective in improving risk factor control after stroke, it may serve as a model that can be used internationally to reduce race/ethnic and socioeconomic disparities in stroke in resource-constrained settings.

trial registrationClinicalTrials.gov Identifier NCT01763203 .

Indexed as

Healthcare DisparitiesAdultAgedAged, 80 and overCerebral HemorrhageCommunity Health ServicesHumansIschemic Attack, TransientLos AngelesMiddle AgedOutcome Assessment, Health CareRisk FactorsSafety-net ProvidersSecondary PreventionSingle-Blind MethodStrokeBiomarkersBlood pressureCommunity health workerCoordinated careDisparitiesIntracerebral hemorrhageNINDS Common Data ElementsStrokeTransient ischemic attackVascular risk

Identifiers

PMID28166784
PMCPMC5294765
OpenAlexW2586552959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.