ArticlePharmaceutical biology2017
Potential anti-inflammatory, antioxidant and antimicrobial activities of Sambucus australis.
Article in Pharmaceutical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 62 citations in OpenAlex.
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- Immunostimulant activity of Centella asiatica (ECa 233) on RAW 264.7 macrophages.BMC complementary medicine and therapies · 2026Article
- On the Antimicrobial Potential ofInternational journal of molecular sciences · 2025Article
- Multi-omics Analysis of Klebsiella pneumoniae Revealed Opposing Effects of Rutin and Luteolin on Strain Growth.Current microbiology · 2024Article
- GenusInternational journal of molecular sciences · 2024Review
- Plant stem cell extract from Coffea canephora shows antioxidant, anti-inflammatory, and skin regenerative properties mediated by suppression of nuclear factor-κB.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023Article
- Evaluation of Biological Activity of Natural Compounds: Current Trends and Methods.Molecules (Basel, Switzerland) · 2022Review
- Barrier effect and wound healing activity of the medical device REF-FTP78 in the treatment of gastroesophageal reflux disease.Scientific reports · 2022Article
- Uncovering the Bioactivity of Aurantiochytrium sp.: a Comparison of Extraction Methodologies.Marine biotechnology (New York, N.Y.) · 2022Article
- Quinic acid: a potential antibiofilm agent against clinical resistant Pseudomonas aeruginosa.Chinese medicine · 2021Article
- In vitro and in vivo anti-inflammatory activity and chemical composition of Renealmia petasites Gagnep.Inflammopharmacology · 2021Article
- A Biorefinery Approach to the Biomass of the SeaweedBiomolecules · 2021Article
- Mode of action and determination of antioxidant activity in the dietary sources: An overview.Saudi journal of biological sciences · 2021Review
- Overall assessment of antibiotic substitutes for pigs: a set of meta-analyses.Journal of animal science and biotechnology · 2021Article
- Efficacy and Mechanism of Traditional Medicinal Plants and Bioactive Compounds against Clinically Important Pathogens.Antibiotics (Basel, Switzerland) · 2019Review
- Antiviral activity of Sambucus FormosanaNakai ethanol extract and related phenolic acid constituents against human coronavirus NL63.Virus research · 2019Article
- Fatty acid composition of vegetable oil blend and in vitro effects of pharmacotherapeutical skin care applications.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2019Article
- Extracts from Myrtle Liqueur Processing Waste Modulate Stem Cells Pluripotency under Stressing Conditions.BioMed research international · 2019Article
- Brazilian medicinal plants with corroborated anti-inflammatory activities: a review.Pharmaceutical biology · 2018Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextSambucus australis Cham. & Schltdl. (Adoxaceae) is used in Brazilian folk medicine to treat inflammatory disorders.
objectiveTo evaluate the in vitro anti-inflammatory, antioxidant and antimicrobial properties of S. australis. MATERIALS AND
methodsThe anti-inflammatory activity of ethanol extracts of the leaf and bark of S. australis (1-100 μg/mL) were studied in lipopolysaccharide/interferon γ stimulated murine macrophages RAW 264.7 cells (24 h incubation) by investigating the release of nitric oxide (NO) and tumour necrosis factor-alpha (TNF-α) and in the TNF-α-induced nuclear factor kappa (NF-κB) assay. Minimum inhibitory concentration (MIC) was determined by the microdilution test (24 h incubation). Antioxidant activity was determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP) and the NO scavenging assays. Chemical composition was assessed by LC-MS/MS.
resultsAntioxidant activities in the DPPH (IC DISCUSSION AND
conclusionThe results indicate that the ethanol leaf extract of S. australis exhibit prominent anti-inflammatory effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.