Evidence map›Paper›PMID 28166683›Full record

ReviewAutoimmunity2017

B cell contribution of the CD4

Seung-Chul Choi, Laurence Morel

Open access · greenAbstract readReview
In one paragraph

Review in Autoimmunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Role of the innate and adaptive immune responses in the pathogenesis of systemic lupus erythematosus.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Impact of the Microbiome on the Immune System.Critical reviews in immunology · 2019
    Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Seung-Chul Choia Department of Pathology, Immunology, and Laboratory Medicine , University of Florida , Gainesville , FL , USA.
Laurence Morela Department of Pathology, Immunology, and Laboratory Medicine , University of Florida , Gainesville , FL , USA.
University of Florida · US

Funding

B Cell Development Defects in Murine LupusR01AI058150 · NIAID · UNIVERSITY OF FLORIDA · PI MOREL, LAURENCE · 2004 to 2014
$3.7M
NIAID NIH HHS R01 AI058150
6 · The paper itself

Abstract

Systemic lupus erythematosus is an autoimmune disease in which the effector molecules responsible for tissue damage are antibodies directed against a large number of self-antigens, among which nucleic acids complexed with proteins play a prominent role. These pathogenic autoantibodies are produced by plasma cells differentiated from activated autoreactive B cells, a process that requires complex interactions between multiple components of the immune systems. A key step in the activation of autoreactive B cells is provided by CD4

Indexed as

AnimalsB-LymphocytesCD4-Positive T-LymphocytesCell CommunicationDendritic CellsDisease SusceptibilityHumansInflammationLupus Erythematosus, SystemicLymphocyte ActivationPhenotypeT-Lymphocyte SubsetsB1-a cellsFollicular helper T cellsmarginal zone B cellsTh17Treg

Identifiers

PMID28166683
PMCPMC5569314
OpenAlexW2587212068

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.