Evidence map›Paper›PMID 28166380›Full record

ArticleChembiochem : a European journal of chemical biology2017

Insights from NMR Spectroscopy into the Conformational Properties of Man-9 and Its Recognition by Two HIV Binding Proteins.

Syed Shahzad-Ul-Hussan, Mallika Sastry, Thomas Lemmin, Cinque Soto, Sandra Loesgen, Danielle A Scott, Jack R Davison, Katheryn Lohith, Robert O'Connor, Peter D Kwong and 1 more

Open access · greenAbstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Structural Insights Into ManAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Fluorinated ManJournal of the American Chemical Society · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Syed Shahzad-Ul-HussanLaboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, 8 Center Drive, Bethesda, MD, 20892, USA.
Mallika SastryStructural Biology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, 40 Convent Drive, Bethesda, MD, 20892, USA.
Thomas LemminStructural Biology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, 40 Convent Drive, Bethesda, MD, 20892, USA.
Cinque SotoStructural Biology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, 40 Convent Drive, Bethesda, MD, 20892, USA.
Sandra LoesgenLaboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, 8 Center Drive, Bethesda, MD, 20892, USA.
Danielle A ScottLaboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, 8 Center Drive, Bethesda, MD, 20892, USA.
Jack R DavisonLaboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, 8 Center Drive, Bethesda, MD, 20892, USA.
Katheryn LohithLaboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, 8 Center Drive, Bethesda, MD, 20892, USA.
Robert O'ConnorLaboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, 8 Center Drive, Bethesda, MD, 20892, USA.
Peter D KwongStructural Biology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, 40 Convent Drive, Bethesda, MD, 20892, USA.
Carole A BewleyLaboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, 8 Center Drive, Bethesda, MD, 20892, USA.ORCID 0000-0003-2203-0852
National Institute of Diabetes and Digestive and Kidney Diseases · USNational Institute of Allergy and Infectious Diseases · USLahore University of Management Sciences · PK

Funding

Mechanisms Of Humoral EvasionZIAAI005023 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ZHOU, TONGQING · 2009 to 2025
$18.6M
Discovery, Structural Studies and Biosynthesis of Biologically Active Natural Products and Natural Product-Like InhibitorsZIADK031135 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI BEWLEY, CAROLE · 2009 to 2025
$16.9M
Inhibitors and Probes of HIV-1 Cell FusionZIADK032103 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI BEWLEY, CAROLE · 2009 to 2025
$12.5M
NMR Facility Management and Application Of NMR SpectroscopyZIADK032101 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI BEWLEY, CAROLE · 2009 to 2025
$4.9M
Computational Tools for Structural AnalysisZICAI005112 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI RAWI, REDA · 2010 to 2025
$4.1M
De novo design of alpha-helical bundlesR37GM054616 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DEGRADO, WILLIAM · 2004 to 2013
$3.6M
DE NOVO DESIGN OF ALPHA HELICAL BUNDLESR01GM054616 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DEGRADO, WILLIAM · 1996 to 2016
$2.4M
Inhibitors Of Hiv-1 Cell Fusion And Mycothiol-related EnZ01DK032103 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI BEWLEY, CAROLE · 2000 to 2008
$896k
Intramural NIH HHS Z01 DK032103NIGMS NIH HHS R01 GM054616NIGMS NIH HHS R37 GM054616
6 · The paper itself

Abstract

Man

Indexed as

Magnetic Resonance SpectroscopyA549 CellsBacterial ProteinsCarbohydrate ConformationCarbon RadioisotopesCell Adhesion MoleculesDC-Specific ICAM-3 Grabbing NonintegrinHIV-1HIV Envelope Protein gp120HumansLectins, C-TypeMannansMannose-Binding LectinMicrocystisMolecular Dynamics SimulationNitrogen RadioisotopesBacterial ProteinsCarbon RadioisotopesCell Adhesion MoleculesDC-Specific ICAM-3 Grabbing NonintegrinHIV Envelope Protein gp120Lectins, C-TypeMannansMannose-Binding Lectinmannosyl(9)-N-acetylglucosamine2microvirin protein, Microcystis aeruginosaNitrogen RadioisotopesReceptors, Cell Surfacecarbohydrate recognitionglycan conformationisotopic labelingmolecular dynamicsNMR spectroscopy

Identifiers

PMID28166380
PMCPMC5557091
OpenAlexW2586088120

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.