ArticlePloS one2017
Optimal control and cost-effective analysis of malaria/visceral leishmaniasis co-infection.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
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- Public health impact of current and proposed age-expanded perennial malaria chemoprevention: a modelling study.Scientific reports · 2025Article
- Impact of infectious density-induced additional screening and treatment saturation on COVID-19: Modeling and cost-effective optimal control.Infectious Disease Modelling · 2024Article
- Dual Antitubercular and Antileishmanial Profiles of Quinoxaline Di-Pharmaceuticals (Basel, Switzerland) · 2024Article
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- Cost-effectiveness analysis of COVID-19 intervention policies using a mathematical model: an optimal control approach.Scientific reports · 2024Article
- Sex-structured disease transmission model and control mechanisms for visceral leishmaniasis (VL).PloS one · 2024Article
- A non-linear mathematical model for analysing the impact of COVID-19 disease on higher education in developing countries.Healthcare analytics (New York, N.Y.) · 2023Article
- Expanding the scope of novel 1,2,3-triazole derivatives as new antiparasitic drug candidates.RSC medicinal chemistry · 2023Article
- Optimal control for the complication of Type 2 diabetes: the role of awareness programs by media and treatment.International journal of dynamics and control · 2023Article
- Implicit versus explicit vector management strategies in models for vector-borne disease epidemiology.Journal of mathematical biology · 2022Article
- Optimal control and comprehensive cost-effectiveness analysis for COVID-19.Results in physics · 2022Article
- Modeling and dynamic analysis of novel coronavirus pneumonia (COVID-19) in China.Journal of applied mathematics & computing · 2022Article
- Malaria and COVID-19 co-dynamics: A mathematical model and optimal control.Applied mathematical modelling · 2021Article
- Control of snakebite envenoming: A mathematical modeling study.PLoS neglected tropical diseases · 2021Article
- Sensitivity assessment and optimal economic evaluation of a new COVID-19 compartmental epidemic model with control interventions.Chaos, solitons, and fractals · 2021Article
- Fractional optimal control problem for an age-structured model of COVID-19 transmission.Chaos, solitons, and fractals · 2021Article
- Article
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2 authors.
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Abstract
In this paper, a deterministic model involving the transmission dynamics of malaria/visceral leishmaniasis co-infection is presented and studied. Optimal control theory is then applied to investigate the optimal strategies for curtailing the spread of the diseases using the use of personal protection, indoor residual spraying and culling of infected reservoirs as the system control variables. Various combination strategies were examined so as to investigate the impact of the controls on the spread of the disease. And we investigated the most cost-effective strategy of all the control strategies using three approaches, the infection averted ratio (IAR), the average cost-effectiveness ratio (ACER) and incremental cost-effectiveness ratio (ICER). Our results show that the implementation of the strategy combining all the time dependent control variables is the most cost-effective control strategy. This result is further emphasized by using the results obtained from the cost objective functional, the ACER, and the ICER.
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