ArticleEpidemiology (Cambridge, Mass.)2017
Outcome-wide Epidemiology.
Article in Epidemiology (Cambridge, Mass.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
109 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Life satisfaction and blood pressure: A coordinated analysis of 16 cohorts.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Pooled it
- Systematically exploring repurposing effects of antihypertensives.Pharmacoepidemiology and drug safety · 2022Pooled it
- Health Effects of Religion, Spirituality, and Supernatural Beliefs in Mainland China: A Systematic Review.Journal of religion and health · 2022Pooled it
- Maternal social networks and child nutrition in Belagavi, India: opportunities and risks.Global health action · 2026Article
- The link between life satisfaction and outcome-wide health: evidence from the Canadian Longitudinal Study on Aging.American journal of epidemiology · 2026Article
- Extreme temperature events and hospitalizations for 59 autoimmune diseases in Korea: A nationwide outcome-wide, time-stratified, case-crossover study.Environmental research · 2026Article
- The dynamic interplay between loneliness and health behaviors from adolescence to midlife: A Norwegian population-based cohort study.Psychological medicine · 2026Article
- Paternal perinatal mental health and early child development: An outcome-wide analysis.Infant mental health journal · 2026Article
- Age at menarche and adverse pregnancy and perinatal outcomes: triangulating evidence from multivariable and Mendelian randomization analyses.International journal of epidemiology · 2026Article
- Longitudinal associations of suffering with subsequent multidimensional well-being in the Global Flourishing Study.Communications medicine · 2026Article
- Coordinated outcome-wide analytic methodology for multi-wave analyses of the global flourishing study.BMC global and public health · 2026Article
- Relevance and challenges of exposome studies for environmental health research.Environmental health : a global access science source · 2026Review
- A Framework for Thinking About the Potential Public Health Impact of Epidemiologic Research.Epidemiology (Cambridge, Mass.) · 2026Article
- Causal K-Means Clustering.Journal of the Royal Statistical Society. Series B, Statistical methodology · 2026Article
- The impact of workplace sexual harassment on health and quality of life outcomes among flight attendants: a two-wave longitudinal study.Social psychiatry and psychiatric epidemiology · 2026Article
- Article
- Association of parental education with offspring psychiatric diagnoses, violent crimes, and suicidal behavior: a nationwide Swedish quasi-experimental study.BMC medicine · 2026Article
- Longitudinal associations of dispositional forgivingness with multidimensional well-being: a two-wave outcome-wide analysis in the Global Flourishing Study.Npj mental health research · 2026Article
- Heterogenous long-term health and social outcomes of type 1 diabetes: a full population 30-year observational cohort study.American journal of epidemiology · 2026Observational
- Integrated Patient Digital and Biomimetic Twins for Precision Medicine: A Perspective.Seminars in liver disease · 2025Review
49 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
The author proposes that epidemiologic studies should more often assess the associations of a single exposure with multiple outcomes simultaneously. Such "outcome-wide epidemiology" will be especially important for exposures that may be beneficial for some outcomes but harmful for others. Outcome-wide epidemiology may also be helpful in prioritizing public health recommendations. Methodologically, the conduct of outcome-wide epidemiology will generally be more straightforward than recent proposals for exposure-wide epidemiologic studies, in which the associations between a single outcome and many exposures are assessed simultaneously. Such exposure-wide studies are likely to be subject to numerous biases because of the inability to make simultaneous confounding control and because exposures are likely to affect, and mediate the effects of, other exposures. These problems simplify considerably in an outcome-wide approach when a single exposure is being considered. Moreover, outcome-wide approaches will generally be more useful than exposure-wide approaches in shaping public health recommendations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.