Evidence map›Paper›PMID 28165863›Full record

ReviewGut microbes2017

Dietary fiber and prebiotics and the gastrointestinal microbiota.

Hannah D Holscher

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Gut microbes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 761 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
761citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04611217 narecruitingnot on this mapstarted 2021, after this paper: background citation

Mechanisms Linking Dietary Fiber, the Microbiome and Satiety

TypeinterventionalSponsorUniversity of Missouri-ColumbiaRan2021 to 2025Enrolled88ConditionsDietary FiberArmsDietary fiber: 10-25g, Dietary fiber: 5g
NCT06292949 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effect of Resistant Starch on Symptom Improvement and Intestinal Microbiome in Patients With Functional Constipation

TypeinterventionalSponsorHuaping XieRan2023 to 2024Enrolled30ConditionsConstipationArmsResistant starch
3 · Its place in the literature

Who cites it

761 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Altered molecular signature of the intestinal microbiota in irritable bowel syndrome patients versus healthy controls: An updated systematic review.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
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  14. GutiMeta · 2026
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  20. Effects of Araticum (Food science & nutrition · 2026
    Article

701 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Hannah D Holschera Department of Food Science and Human Nutrition and Division of Nutritional Sciences , University of Illinois , 361 Edward R. Madigan Laboratory, Urbana , IL USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gastrointestinal microbiota has an important role in human health, and there is increasing interest in utilizing dietary approaches to modulate the composition and metabolic function of the microbial communities that colonize the gastrointestinal tract to improve health, and prevent or treat disease. One dietary strategy for modulating the microbiota is consumption of dietary fiber and prebiotics that can be metabolized by microbes in the gastrointestinal tract. Human alimentary enzymes are not able to digest most complex carbohydrates and plant polysaccharides. Instead, these polysaccharides are metabolized by microbes which generate short-chain fatty acids (SCFAs), including acetate, propionate, and butyrate. This article reviews the current knowledge of the impact of fiber and prebiotic consumption on the composition and metabolic function of the human gastrointestinal microbiota, including the effects of physiochemical properties of complex carbohydrates, adequate intake and treatment dosages, and the phenotypic responses related to the composition of the human microbiota.

Indexed as

Gastrointestinal MicrobiomeAnimalsBacteriaDietary FiberGastrointestinal TractHumansPrebioticsDietary FiberPrebioticsfermentationhuman microbiomenon-digestible carbohydrateshort-chain fatty acids

Identifiers

PMID28165863
PMCPMC5390821

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.