Evidence map›Paper›PMID 28165833›Full record

ArticleDrug delivery2017

Diclofenac sodium ion exchange resin complex loaded melt cast films for sustained release ocular delivery.

Goutham R Adelli, Sai Prachetan Balguri, Prakash Bhagav, Vijayasankar Raman, Soumyajit Majumdar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug delivery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Gellan Gum BasedThe Journal of pharmacology and experimental therapeutics · 2019
    Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Goutham R Adellia Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, University , MS , USA.
Sai Prachetan Balguria Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, University , MS , USA.
Prakash Bhagava Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, University , MS , USA.
Vijayasankar Ramanb National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University , MS , USA , and.
Soumyajit Majumdara Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, University , MS , USA.

Funding

Evaluation and Inhibition of Efflux Pumps Expressed on the Blood Ocular BarrierR01EY022120 · NEI · UNIVERSITY OF MISSISSIPPI · PI MAJUMDAR, SOUMYAJIT · 2015 to 2018
$1.5M
NEI NIH HHS R01 EY022120
6 · The paper itself

Abstract

purposeThe goal of the present study is to develop polymeric matrix films loaded with a combination of free diclofenac sodium (DFS

methodsEffect of ratio of DFS and IR on the DFS:IR complexation efficiency was studied using batch processing. DFS:IR complex, DFS

resultsComplexation efficiency of DFS:IR was found to be 99% with a 1:1 ratio of DFS:IR. DFS release from DFS:IR suspension and the film were best-fit to a Higuchi model. In vitro transcorneal flux with the DFS

conclusionDFS

Indexed as

Administration, OphthalmicAdministration, TopicalAnimalsChemistry, PharmaceuticalDelayed-Action PreparationsDiclofenacDrug Delivery SystemsEyeIon Exchange ResinsMaleOphthalmic SolutionsOrgan Culture TechniquesRabbitsDelayed-Action PreparationsDiclofenacIon Exchange ResinsOphthalmic Solutionsdiclofenac sodium and polymeric matrix filmsimmediate release formulationsIon exchange resinsocular drug delivery

Identifiers

PMID28165833
PMCPMC8253122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.