Evidence map›Paper›PMID 28165484›Full record

ArticleScientific reports2017

New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex.

A Ishchenko, E Round, V Borshchevskiy, S Grudinin, I Gushchin, J P Klare, A Remeeva, V Polovinkin, P Utrobin, T Balandin and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Signal transduction in photoreceptor histidine kinases.Protein science : a publication of the Protein Society · 2019
    Review
  10. Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 3 countries.

A IshchenkoInstitute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Jülich, 52425 Jülich, Germany.
E RoundInstitute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Jülich, 52425 Jülich, Germany.
V BorshchevskiyInstitute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Jülich, 52425 Jülich, Germany.
S GrudininCNRS, Laboratoire Jean Kuntzmann, BP 53, Grenoble Cedex 9, France.
I GushchinInstitute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Jülich, 52425 Jülich, Germany.
J P KlareMax-Planck Institute of Molecular Physiology, 44227 Dortmund, Germany.
A RemeevaInstitute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Jülich, 52425 Jülich, Germany.
V PolovinkinInstitute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Jülich, 52425 Jülich, Germany.
P UtrobinMoscow Institute of Physics and Technology, 141700 Dolgoprudniy, Russia.
T BalandinInstitute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Jülich, 52425 Jülich, Germany.
M EngelhardMax-Planck Institute of Molecular Physiology, 44227 Dortmund, Germany.
G BüldtInstitute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Jülich, 52425 Jülich, Germany.
V GordeliyInstitute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Jülich, 52425 Jülich, Germany.
Forschungszentrum Jülich · DECentre National de la Recherche Scientifique · FRCEA Grenoble · FRInstitut de Biologie Structurale · FRMax Planck Institute of Molecular Physiology · DEMoscow Institute of Physics and Technology · RUOsnabrück University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complex of two membrane proteins, sensory rhodopsin II (NpSRII) with its cognate transducer (NpHtrII), mediates negative phototaxis in halobacteria N. pharaonis. Upon light activation NpSRII triggers a signal transduction chain homologous to the two-component system in eubacterial chemotaxis. Here we report on crystal structures of the ground and active M-state of the complex in the space group I2

Indexed as

Signal TransductionArchaeal ProteinsBinding SitesHalobacteriaceaeMagnetic Resonance SpectroscopyModels, MolecularProtein BindingProtein ConformationProtein Interaction Domains and MotifsProtein MultimerizationSensory RhodopsinsStatic ElectricityStructure-Activity RelationshipArchaeal ProteinsSensory Rhodopsins

Identifiers

PMID28165484
PMCPMC5292967
OpenAlexW2587298707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.