Evidence map›Paper›PMID 28165453›Full record

ArticleNature microbiology2017

Architecture of the Vibrio cholerae toxin-coregulated pilus machine revealed by electron cryotomography.

Yi-Wei Chang, Andreas Kjær, Davi R Ortega, Gabriela Kovacikova, John A Sutherland, Lee A Rettberg, Ronald K Taylor, Grant J Jensen

Abstract read
In one paragraph

Article in Nature microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Article
  2. mBio · 2026
    Article
  3. Article
  4. Article
  5. Electron Cryo-Tomography Reveals thebioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Integrative Structure and Function of thebioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Type IV pili ofEcoSal Plus · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. End-to-end robust joint unsupervised image alignment and clustering.Proceedings. IEEE International Conference on Computer Vision · 2021
    Article
  20. The polar Ras-like GTPase MglA activates type IV pilus via SgmX to enable twitching motility inProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yi-Wei ChangCalifornia Institute of Technology, Pasadena, California 91125, USA.
Andreas KjærUniversity of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark.
Davi R OrtegaCalifornia Institute of Technology, Pasadena, California 91125, USA.
Gabriela KovacikovaGeisel School of Medicine at Dartmouth, Hanover, New Hampshire 03755, USA.
John A SutherlandGeisel School of Medicine at Dartmouth, Hanover, New Hampshire 03755, USA.
Lee A RettbergHoward Hughes Medical Institute, Pasadena, California 91125, USA.
Ronald K TaylorGeisel School of Medicine at Dartmouth, Hanover, New Hampshire 03755, USA.
Grant J JensenCalifornia Institute of Technology, Pasadena, California 91125, USA.

Funding

Structure and Function of Pathogenesis-Associated Bacterial Structures by Electron CryotomographyR01AI127401 · NIAID · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI GRANT J JENSEN · 2016 to 2026
$3.9M
GENTICS DETERMINATION OF VIRULENCE OF VIBRIO CHOLERAER01AI025096 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI SKORUPSKI, KAREN A · 1989 to 2016
$3.1M
Structure and function of the prokaryotic cytoskeleton by electron cryotomographyR01GM094800 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI JENSEN, GRANT J · 2011 to 2015
$1.7M
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI025096NIAID NIH HHS R01 AI127401NIGMS NIH HHS R01 GM094800
6 · The paper itself

Abstract

Type IV pili (T4P) are filamentous appendages found on many Bacteria and Archaea. They are helical fibres of pilin proteins assembled by a multi-component macromolecular machine we call the basal body. Based on pilin features, T4P are classified into type IVa pili (T4aP) and type IVb pili (T4bP)

Indexed as

Bacterial AdhesionBacterial ProteinsCholera ToxinElectron Microscope TomographyFimbriae, BacterialFimbriae ProteinsModels, MolecularMutationMyxococcus xanthusVibrio choleraeBacterial ProteinsCholera ToxinFimbriae Proteins

Identifiers

PMID28165453
PMCPMC5302817

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.