ReviewBiology2017
Circadian Rhythms and Hormonal Homeostasis: Pathophysiological Implications.
Review in Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
96 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Human melanopsin (OPN4) gene polymorphisms: a systematic review.Frontiers in neuroscience · 2025Pooled it
- Physiological Rhythms and Biological Variation of Biomolecules: The Road to Personalized Laboratory Medicine.International journal of molecular sciences · 2023Pooled it
- Eating jetlag based on meal timing discrepancies and risk of cardiovascular disease using the prospective cohort NutriNet-Santé.Communications medicine · 2026Article
- Causal association between oral microbiota and hepatocellular carcinoma in East Asian populations: a Mendelian randomization study.Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026Article
- Infra-slow (<0.1 Hz) Modulation of Human Brain Pulsations in Awake and Sleep States.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Sleep and Sleep Disorder Knowledge Among Physicians Working in Qatar's Primary Health Care Corporation: A Cross-Sectional Study.Clocks & sleep · 2026Article
- Circadian patterns of patient symptoms in a tertiary university emergency department: a single-centre retrospective analysis.BMJ open · 2026Article
- Identification and Validation of RORC as a Circadian Rhythm-Related Biomarker in Gastric Cancer.International journal of general medicine · 2026Article
- Non-chemical, chemical, and biochemical, endocrine disruptors: biphasic health effects and pathophysiological insights.Frontiers in endocrinology · 2026Review
- Article
- The Circadian Modulators as Molecular Targets in Cancer-A Review.International journal of molecular sciences · 2025Review
- Chronotype, Night Shift Work, and Diurnal Salivary Cortisol Rhythms Among Healthcare Professionals.Journal of clinical medicine · 2025Article
- Exploring the connection between the Mitochondrial DNA and the Circadian Rhythm: Insights into Mitochondrial Biogenesis and its Dynamics.Molecular biology reports · 2025Review
- Multifaceted dynamics of circadian timing system influence aging and longevity.Biogerontology · 2025Review
- Environmental and biological drivers of movement activity in Callimico goeldii under zoo conditions.Scientific reports · 2025Article
- Established dietary interventions and time-restricted eating for cardiovascular disease prevention.Cell reports. Medicine · 2025Review
- Sleep Irregularity, Circadian Disruption, and Cardiometabolic Disease Risk.Circulation research · 2025Review
- Comparative analysis of morning and evening training on performance and well-being in elite soccer players.Physiological reports · 2025Article
- Effect of gestational exposure to dim light at night on the behavior of rat dams and offspring.Scientific reports · 2025Article
- The estrous cycle modulates hippocampal spine dynamics, dendritic processing, and spatial coding.Neuron · 2025Article
36 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation of our physiology, including hormonal and metabolic homeostasis. Here we will review the structure, organisation and molecular machinery that make our circadian clock work, and its relevance for the proper functioning of physiological processes. We will also describe the interconnections between circadian rhythms and endocrine homeostasis, as well as the underlying consequences that circadian dysregulations might have in the development of several pathologic affections. Finally, we will discuss how a better knowledge of such relationships might prove helpful in designing new therapeutic approaches for endocrine and metabolic diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.