ArticleInternational journal of molecular sciences2017
Behavior of Gingival Fibroblasts on Titanium Implant Surfaces in Combination with either Injectable-PRF or PRP.
Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 58 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Effectiveness of a Topical Subgingival Application of Injectable Platelet-rich Fibrin as Adjunctive Therapy to Scaling and Root Planing. A Double-blind Split Mouth Randomized Prospective Comparative Controlled Trial
Efficiency of Hyaluronic Acid Versus Red Injectable Platelet-Rich Fibrin (i-PRF) in Treatment of Stage III Periodontitis (Randomized Controlled Clinical Trial)
Who cites it
58 citing papers in PubMed, 4 syntheses or guidelines pooled it, 132 citations in OpenAlex.
- Platelet-rich plasma (PRP) versus injectable platelet-rich fibrin (i-PRF): A systematic review across all fields of medicine.Periodontology 2000 · 2025Pooled it
- Hyaluronic acid as a promoter of the healing of post-extraction socket treated with the socket preservation technique: a systematic review.Frontiers in oral health · 2025Pooled it
- Effect of platelet concentrates for pain and symptom management in oral lichen planus: an evidence-based systematic review.BMC oral health · 2023Pooled it
- Effect of platelet-rich fibrin on cell proliferation, migration, differentiation, inflammation, and osteoclastogenesis: a systematic review of in vitro studies.Clinical oral investigations · 2020Pooled it
- The efficacy of injectable platelet-rich fibrin versus photobiomodulation therapy on palatal wound healing: a randomized, controlled, clinical trial.Clinical oral investigations · 2025Trial
- Liquid platelet-rich fibrin in root surface biomodification during gingival recession treatment: Randomized, controlled, split-mouth, clinical trial.Clinical and experimental dental research · 2023Trial
- Guided bone regeneration simultaneous with implant placement using bovine-derived xenograft with and without liquid platelet-rich fibrin: a randomized controlled clinical trial.Clinical oral investigations · 2021Trial
- Comparison of the effects of injectable platelet-rich fibrin and autologous fibrin glue applications on palatal wound healing: a randomized controlled clinical trial.Clinical oral investigations · 2020Trial
- Correction: Wang et al. Behavior of Gingival Fibroblasts on Titanium Implant Surfaces in Combination with Either Injectable-PRF or PRP.International journal of molecular sciences · 2026Article
- Adjunctive Use of Platelet-Derived Concentrates (Platelet-Rich Plasma, Platelet-Rich Fibrin, Concentrated Growth Factor, Platelet-Poor Plasma) in Non-Surgical Periodontal Therapy: Current Evidence and Comparative Analysis.Journal of clinical medicine · 2026Review
- Platelet-Rich Fibrin and Its Derivatives as Adjuncts to Dental Implant Osseointegration: A Scoping Review.International journal of dentistry · 2026Review
- Biomolecule-functionalized dental implant surfaces: Towards augmenting soft tissue integration.Bioactive materials · 2025Review
- Role of Mesenchymal Stem Cell Exosomes and Injectable Platelet Rich Fibrin on Structure and Function of Submandibular Salivary Gland of Aged Albino Rats.The Saudi dental journal · 2025Article
- The effect of liquid platelet-rich fibrin on oral cells and tissue engineered oral mucosa models in vitro.Scientific reports · 2025Article
- Effects of i-PRF, A-PRF+, and EMD on Osteogenic Potential of Osteoblasts on Titanium.Clinical implant dentistry and related research · 2025Article
- A Comparison of the Dimensional Characteristics and Plasma Parameters of Different Centrifuges Used for the Preparation of Autologous Platelet Concentrates: A Randomized Correlational Study.Materials (Basel, Switzerland) · 2025Article
- A prospective evaluation of subgingival irrigation with i-PRF following non-surgical treatment of peri-implantitis.Frontiers in dental medicine · 2025Article
- A comparative study of three liquid platelet concentrates on human primary osteoblast activity: an in vitro study.Journal of applied oral science : revista FOB · 2025Article
- Effect of Liquid Blood Concentrates on Cell Proliferation and Cell Cycle- and Apoptosis-Related Gene Expressions in Nonmelanoma Skin Cancer Cells: A Comparative In Vitro Study.International journal of molecular sciences · 2024Article
- Focuses and Trends of Research on Platelet-Rich Fibrin: A Bibliometric and Visual Analysis.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Various strategies have been employed to speed tissue regeneration using bioactive molecules. Interestingly, platelet concentrates derived from a patient's own blood have been utilized as a regenerative strategy in recent years. In the present study, a novel liquid platelet formulation prepared without the use of anti-coagulants (injectable-platelet-rich fibrin, i-PRF) was compared to standard platelet-rich plasma (PRP) with gingival fibroblasts cultured on smooth and roughened titanium implant surfaces. Standard PRP and i-PRF (centrifuged at 700 rpm (60×
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.