Evidence map›Paper›PMID 28165218›Full record

ArticleBiochemistry2017

Perfluoro-tert-butyl Homoserine Is a Helix-Promoting, Highly Fluorinated, NMR-Sensitive Aliphatic Amino Acid: Detection of the Estrogen Receptor·Coactivator Protein-Protein Interaction by

Caitlin M Tressler, Neal J Zondlo

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 32 citations in OpenAlex.

  1. Analytical chemistry · 2026
    Article
  2. Article
  3. RSC chemical biology · 2021
    Review
  4. Article
  5. Beilstein journal of organic chemistry · 2021
    Review
  6. Perfluorocarbons in Chemical Biology.Chembiochem : a European journal of chemical biology · 2020
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Caitlin M TresslerDepartment of Chemistry and Biochemistry, University of Delaware , Newark, Delaware 19716, United States.
Neal J ZondloDepartment of Chemistry and Biochemistry, University of Delaware , Newark, Delaware 19716, United States.ORCID 0000-0002-7417-8085
University of Delaware · US

Funding

Pilot Research Subproject ProgramP30GM110758 · NIGMS · UNIVERSITY OF DELAWARE · PI BEEBE, THOMAS PAUL · 2014 to 2018
$5.8M
Novel Protein SensorsR01GM093225 · NIGMS · UNIVERSITY OF DELAWARE · PI ZONDLO, NEAL J · 2010 to 2014
$1.4M
NIGMS NIH HHS P30 GM110758NIGMS NIH HHS R01 GM093225
6 · The paper itself

Abstract

Highly fluorinated amino acids can stabilize proteins and complexes with proteins, via enhanced hydrophobicity, and provide novel methods for identification of specific molecular events in complex solutions, via selective detection by

Indexed as

HalogenationAmino Acid SequenceEstrogen Receptor alphaFluorocarbonsHomoserineHumansMagnetic Resonance SpectroscopyModels, MolecularProtein BindingProtein Conformation, alpha-HelicalProtein DomainsEstrogen Receptor alphaFluorocarbonsHomoserineperfluoro-tert-butyl homoserine

Identifiers

PMID28165218
PMCPMC5894335
OpenAlexW2587305690

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.