ArticleScientific reports2017
Light-sheet fluorescence imaging to localize cardiac lineage and protein distribution.
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Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27citing papers in PubMed
9.8field-weighted citation impact, top 2% of its field
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Who cites it
27 citing papers in PubMed, 53 citations in OpenAlex.
- Refractive Index-Corrected Light-Sheet Microscopy for Macro-View Cardiovascular Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Metalens-Based Dual Light-Sheet Fluorescence Microscopy.Small methods · 2025Article
- Frontiers in artificial intelligence-directed light-sheet microscopy for uncovering biological phenomena and multi-organ imaging.View (Beijing, China) · 2024Article
- A practical guide to light-sheet microscopy for nanoscale imaging: Looking beyond the cell.Journal of applied physics · 2024Article
- Light-Sheet Imaging to Reveal Cardiac Structure in Rodent Hearts.Journal of visualized experiments : JoVE · 2024Article
- Management of autofluorescence in formaldehyde-fixed myocardium: choosing the right treatment.European journal of histochemistry : EJH · 2023Article
- Light sheet imaging and interactive analysis of the cardiac structure in neonatal mice.Journal of biophotonics · 2023Article
- Review
- Scale space detector for analyzing spatiotemporal ventricular contractility and nuclear morphogenesis in zebrafish.iScience · 2022Article
- Development of Planar Illumination Strategies for Solving Mysteries in the Sub-Cellular Realm.International journal of molecular sciences · 2022Review
- Conventional histomorphometry and fast free of acrylamide clearing tissue (FACT) visualization of sciatic nerve in chicken (Veterinary research forum : an international quarterly journal · 2021Article
- Saak Transform-Based Machine Learning for Light-Sheet Imaging of Cardiac Trabeculation.IEEE transactions on bio-medical engineering · 2021Article
- Three-dimensional Imaging Coupled with Topological Quantification Uncovers Retinal Vascular Plexuses Undergoing Obliteration.Theranostics · 2021Article
- Correcting anisotropic intensity in light sheet images using dehazing and image morphology.APL bioengineering · 2020Article
- Imaging of the immune system - towards a subcellular and molecular understanding.Journal of cell science · 2020Review
- Three-Dimensional Imaging Provides Detailed Atherosclerotic Plaque Morphology and Reveals Angiogenesis After Carotid Artery Ligation.Circulation research · 2020Article
- Advanced microscopy to elucidate cardiovascular injury and regeneration: 4D light-sheet imaging.Progress in biophysics and molecular biology · 2018Review
- Ultrafast Volumetric Optoacoustic Imaging of Whole Isolated Beating Mouse Heart.Scientific reports · 2018Article
- Light-sheet Fluorescence Microscopy for the Study of the Murine Heart.Journal of visualized experiments : JoVE · 2018Article
- A Langendorff-like system to quantify cardiac pump function in adult zebrafish.Disease models & mechanisms · 2018Article
Corrections and comments
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Authors and funding
14 authors at 6 institutions in 2 countries.
Yichen DingDivision of Cardiology, Department of Medicine, UCLA, Los Angeles, CA 90095, USA.
Juhyun LeeDepartment of Bioengineering, School of Engineering &Applied Sciences, UCLA, Los Angeles, CA 90095, USA.
Jianguo MaDivision of Cardiology, Department of Medicine, UCLA, Los Angeles, CA 90095, USA.
Kevin SungDepartment of Bioengineering, School of Engineering &Applied Sciences, UCLA, Los Angeles, CA 90095, USA.
Tomohiro YokotaDepartments of Anesthesiology, Physiology and Medicine, Cardiovascular Research Laboratories, UCLA, Los Angeles, CA 90095, USA.
Neha SinghDivision of Cardiology, Department of Medicine, UCLA, Los Angeles, CA 90095, USA.
Mojdeh DooraghiDivision of Cardiology, Department of Medicine, UCLA, Los Angeles, CA 90095, USA.
Parinaz AbiriDivision of Cardiology, Department of Medicine, UCLA, Los Angeles, CA 90095, USA.
Yibin WangDepartments of Anesthesiology, Physiology and Medicine, Cardiovascular Research Laboratories, UCLA, Los Angeles, CA 90095, USA.
Rajan P KulkarniDepartment of Bioengineering, School of Engineering &Applied Sciences, UCLA, Los Angeles, CA 90095, USA.
Atsushi NakanoDepartment of Molecular, Cellular and Developmental Biology, UCLA, Los Angeles, CA 90095, USA.
Thao P NguyenDivision of Cardiology, Department of Medicine, UCLA, Los Angeles, CA 90095, USA.
Peng FeiSchool of Optical and Electronic Information, Huazhong University of Science and Technology, Wuhan, China.
Tzung K HsiaiDivision of Cardiology, Department of Medicine, UCLA, Los Angeles, CA 90095, USA.
University of California, Los Angeles · USLa Jolla Bioengineering Institute · USUCLA Medical Center · USBroad Center · USHuazhong University of Science and Technology · CNUCLA Health · US
Funding
UCLA-Caltech Medical Scientist Training ProgramT32GM008042 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AJIJOLA, OLUJIMI A, DAWSON, DAVID WAYNE · 1985 to 2023
$29.9MA Resource on Medical Ultrasonic Transducer TechnologyP41EB002182 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SHUNG, K KIRK · 2003 to 2016
$13.3MThe Effect of Nanoparticle Encapsulated Resveratrol on Treatment of PeriodontitisKL2TR001882 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Elizabeta Nemeth · 2016 to 2026
$13.1MThe Los Angeles PRISMS Center: The Biomedical REAl-Time Health Evaluation (BREATHE) PlatformU54EB022002 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BUI, ALEX · 2015 to 2016
$6.1MUCLA Clinical and Translational Science InstituteKL2TR000122 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$4.5MLinking Spatial Variations Shear Stress-Oxidative StressR01HL083015 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HSIAI, TZUNG K · 2006 to 2015
$3.9MShear Stress and Light-Sheets to Study Cardiac TrabeculationR01HL129727 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HSIAI, TZUNG K, MARSDEN, ALISON L · 2015 to 2024
$3.5MElectronica Impedance to Access Metabolically Active PlaqueR01HL118650 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HSIAI, TZUNG K · 2014 to 2022
$3.3MMicro-Sensors to Study Electrical and Mechanical Coupling of Injured MyocardiumR01HL111437 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HSIAI, TZUNG K, XU, XIAOLEI · 2012 to 2020
$3.1MNCATS NIH HHS KL2 TR000122NCATS NIH HHS KL2 TR001882NHLBI NIH HHS R01 HL083015NHLBI NIH HHS R01 HL111437NHLBI NIH HHS R01 HL118650NHLBI NIH HHS R01 HL129727NIBIB NIH HHS P41 EB002182NIBIB NIH HHS U54 EB022002
Abstract
Light-sheet fluorescence microscopy (LSFM) serves to advance developmental research and regenerative medicine. Coupled with the paralleled advances in fluorescence-friendly tissue clearing technique, our cardiac LSFM enables dual-sided illumination to rapidly uncover the architecture of murine hearts over 10 by 10 by 10 mm
Indexed as
Imaging, Three-DimensionalAnimalsAnimals, NewbornCalibrationCell LineageFluorescenceGreen Fluorescent ProteinsHeart VentriclesMiceMicroscopy, FluorescenceMyocardiumPotassium ChannelsProteinsGreen Fluorescent ProteinsPotassium ChannelsProteins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.