Evidence map›Paper›PMID 28164936›Full record

ArticleNoise & health

The Effects of Acoustic White Noise on the Rat Central Auditory System During the Fetal and Critical Neonatal Periods: A Stereological Study.

Mohammad Saied Salehi, Mohammad Reza Namavar, Amin Tamadon, Raziyeh Bahmani, Mohammad Reza Jafarzadeh Shirazi, Homayoun Khazali, Leila Dargahi, Sareh Pandamooz, Farzad Mohammad-Rezazadeh, Fatemeh Sadat Rashidi

Abstract read
In one paragraph

Article in Noise & health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mohammad Saied SalehiDepartment of Physiology, Faculty of Biological Sciences and Technology, Shahid Beheshti University, Tehran; Department of Animal Sciences, College of Agriculture, Shiraz University, Shiraz, Iran.
Mohammad Reza NamavarHistomorphometry and Stereology Research Center, Shiraz University of Medical Sciences, Shiraz; Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Amin TamadonTransgenic Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Raziyeh BahmaniDepartment of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Reza Jafarzadeh ShiraziDepartment of Animal Sciences, College of Agriculture, Shiraz University, Shiraz, Iran.
Homayoun KhazaliDepartment of Physiology, Faculty of Biological Sciences and Technology, Shahid Beheshti University, Tehran, Iran.
Leila DargahiNeuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sareh PandamoozNeuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Farzad Mohammad-RezazadehDepartment of Animal Sciences, College of Agriculture, Shiraz University, Shiraz, Iran.
Fatemeh Sadat RashidiNeuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the effects of long-term, moderate level noise exposure during crucial periods of rat infants on stereological parameters of medial geniculate body (MGB) and auditory cortex. MATERIALS AND

methodsTwenty-four male offspring of 12 pregnant rats were divided into four groups: fetal-to-critical period group, which were exposed to noise from the last 10 days of fetal life till postnatal day (PND) 29; fetal period group that exposed to noise during the last 10 days of fetal life; critical period group, exposed to noise from PND 15 till PND 29, and control group. White noise at 90 dB for 2 h per day was used. STATISTICAL ANALYSIS USED: Variance for variables was performed using Proc GLM followed by mean comparison by Duncan's multiple range test.

resultsNumerical density of neurons in MGB of fetal-to-critical period group was lower than control group. Similar results were seen in numerical density of neurons in layers IV and VI of auditory cortex. Furthermore, no significant difference was observed in the volume of auditory cortex among groups, and only MGB volume in fetal-to-critical period group was higher than other groups. Estimated total number of neurons in MGB was not significantly different among groups.

conclusionIt seems necessary to prevent long-term moderate level noise exposure during fetal-to-critical neonatal period.

Indexed as

NoiseAnimalsAnimals, NewbornAuditory CortexCell CountFemaleFetal DevelopmentGeniculate BodiesMaleNeuronsPregnancyRats

Identifiers

PMID28164936
PMCPMC5397999

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.