ArticleAngewandte Chemie (International ed. in English)2017
Automated Synthesis of Well-Defined Polymers and Biohybrids by Atom Transfer Radical Polymerization Using a DNA Synthesizer.
Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- RNA-Polymer Conjugates via Direct Incorporation of the Chain Transfer Agent and PET-RAFT Polymerization.Biomacromolecules · 2025Article
- Artificial Zymogen Based on Protein-Polymer Hybrids.Biomacromolecules · 2024Article
- Solid-Phase Synthesis of Well-Defined Multiblock Copolymers by Atom Transfer Radical Polymerization.Journal of the American Chemical Society · 2024Article
- Beyond Lipids: Exploring Advances in Polymeric Gene Delivery in the Lipid Nanoparticles Era.Advanced materials (Deerfield Beach, Fla.) · 2024Review
- Highly Sensitive Detection of Bacteria by Binder-Coupled Multifunctional Polymeric Dyes.Polymers · 2023Article
- Fully Oxygen-Tolerant Visible-Light-Induced ATRP of Acrylates in Water: Toward Synthesis of Protein-Polymer Hybrids.Macromolecules · 2023Article
- Open-air green-light-driven ATRP enabled by dual photoredox/copper catalysis.Chemical science · 2022Article
- Toward Green Atom Transfer Radical Polymerization: Current Status and Future Challenges.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Cytochrome C catalyzed oxygen tolerant atom-transfer radical polymerization.Bioresources and bioprocessing · 2022Article
- Functional DNA-Polymer Conjugates.Chemical reviews · 2021Review
- Microwave-Assisted Automated Glycan Assembly.Journal of the American Chemical Society · 2021Article
- DNA-polymer conjugatesChemical communications (Cambridge, England) · 2021Article
- Synthetic Approaches for Copolymers Containing Nucleic Acids and Analogues: Challenges and Opportunities.Polymer chemistry · 2021Article
- Engineering exosome polymer hybrids by atom transfer radical polymerization.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- DNA Functional Nanomaterials for Controlled Delivery of Nucleic Acid-Based Drugs.Frontiers in bioengineering and biotechnology · 2021Review
- Electro-Mechanochemical Atom Transfer Radical Cyclizations using Piezoelectric BaTiOAngewandte Chemie (International ed. in English) · 2020Article
- DNA-Polymer Nanostructures by RAFT Polymerization and Polymerization-Induced Self-Assembly.Angewandte Chemie (International ed. in English) · 2020Article
- Fully oxygen-tolerant atom transfer radical polymerization triggered by sodium pyruvate.Chemical science · 2020Article
- Hydrophobic Interaction: A Promising Driving Force for the Biomedical Applications of Nucleic Acids.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Review
- Enlightening advances in polymer bioconjugate chemistry: light-based techniques for grafting to and from biomacromolecules.Chemical science · 2020Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
A DNA synthesizer was successfully employed for preparation of well-defined polymers by atom transfer radical polymerization (ATRP), in a technique termed AutoATRP. This method provides well-defined homopolymers, diblock copolymers, and biohybrids under automated photomediated ATRP conditions. PhotoATRP was selected over other ATRP methods because of mild reaction conditions, ambient temperature, tolerance to oxygen, and no need to introduce reducing agents or radical initiators. Both acrylate and methacrylate monomers were successfully polymerized with excellent control in the DNA synthesizer. Diblock copolymers were synthesized with different targeted degrees of polymerization and with high retention of chain-end functionality. Both hydrophobic and hydrophilic monomers were grafted from DNA. The DNA-polymer hybrids were characterized by SEC and DLS. The AutoATRP method provides an efficient route to prepare a range of different polymeric materials, especially polymer-biohybrids.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.