Evidence map›Paper›PMID 28164421›Full record

ReviewMicrocirculation (New York, N.Y. : 1994)2017

Tissue-engineered 3D microvessel and capillary network models for the study of vascular phenomena.

Max I Bogorad, Jackson DeStefano, Andrew D Wong, Peter C Searson

Abstract readReview
In one paragraph

Review in Microcirculation (New York, N.Y. : 1994), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Modular cone-and-plate device for mechanofluidic assays in Transwell inserts.Frontiers in bioengineering and biotechnology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Vascularized Biomaterials to Study Cancer Metastasis.Advanced healthcare materials · 2020
    Review
  15. Recapitulating the Vasculature Using Organ-On-Chip Technology.Bioengineering (Basel, Switzerland) · 2020
    Review
  16. Microfluidic endothelium-on-a-chip development, from in vivo to in vitro experimental models.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Max I BogoradInstitute for Nanobiotechnology (INBT), Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0001-7774-6888
Jackson DeStefanoInstitute for Nanobiotechnology (INBT), Johns Hopkins University, Baltimore, MD, USA.
Andrew D WongInstitute for Nanobiotechnology (INBT), Johns Hopkins University, Baltimore, MD, USA.
Peter C SearsonInstitute for Nanobiotechnology (INBT), Johns Hopkins University, Baltimore, MD, USA.

Funding

T32: Predoctoral and Postdoctoral Training Program in Nanotechnology for Cancer ResearchT32CA153952 · NCI · JOHNS HOPKINS UNIVERSITY · PI Denis Wirtz · 2015 to 2026
$3.5M
Mechanisms of cerebrovascular barrier dysfunction caused by APP and PSEN1 mutations and amyloid beta exposureR01NS106008 · NINDS · JOHNS HOPKINS UNIVERSITY · PI SEARSON, PETER C · 2019 to 2023
$1.9M
T-32 NIH Postdoctoral Training Program in Nanotechnology for Cancer Medicine NTCMT32CA130840 · NCI · JOHNS HOPKINS UNIVERSITY · PI WIRTZ, DENIS · 2008 to 2012
$1.2M
NCI NIH HHS T32 CA130840NCI NIH HHS T32 CA153952NINDS NIH HHS R01 NS106008
6 · The paper itself

Abstract

Advances in tissue engineering, cell biology, microfabrication, and microfluidics have led to the development of a wide range of vascular models. Here, we review platforms based on templated microvessel fabrication to generate increasingly complex vascular models of (i) the tumor microenvironment, (ii) occluded microvessels, and (iii) perfused capillary networks. We outline fabrication guidelines and demonstrate a number of experimental methods for probing vascular function such as permeability measurements, tumor cell intravasation, flow characterization, and endothelial cell morphology and proliferation.

Indexed as

MicrovesselsModels, CardiovascularEndothelium, VascularHumansTissue Engineeringcapillary networksmetastasismicrofabricationmicrofluidicsmicrovascular modelsself-organizationtemplatingvessel occlusion

Identifiers

PMID28164421
PMCPMC6726128

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.