Evidence map›Paper›PMID 28164205›Full record

ArticleIntegrative biology : quantitative biosciences from nano to macro2017

Single-cell resolution of intracellular T cell Ca

Ariel S Kniss-James, Catherine A Rivet, Loice Chingozha, Hang Lu, Melissa L Kemp

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Integrative biology : quantitative biosciences from nano to macro, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Engineering Approaches to Study Cellular Decision Making.Annual review of biomedical engineering · 2018
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ariel S Kniss-JamesThe Parker H. Petit Institute of Bioengineering and Bioscience, Georgia Institute of Technology, 315 Ferst Dr NW, Atlanta, GA 30332-0363, USA.
Catherine A Rivet
Loice Chingozha
Hang Lu
Melissa L Kemp

Funding

Spatiotemporal control of reactive oxygen species in T cellsR01AI088023 · NIAID · GEORGIA INSTITUTE OF TECHNOLOGY · PI KEMP, MELISSA LAMBETH · 2011 to 2014
$1.4M
A Computational Biology and Predictive Health Genomics Training Program at GTT32GM105490 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI GIBSON, GREGORY C · 2014 to 2018
$901k
Spatiotemporal control of reactive oxygen species in T cellsR56AI088023 · NIAID · GEORGIA INSTITUTE OF TECHNOLOGY · PI KEMP, MELISSA LAMBETH, LU, HANG · 2015 to 2015
$371k
NIAID NIH HHS R01 AI088023NIAID NIH HHS R56 AI088023NIGMS NIH HHS T32 GM105490
6 · The paper itself

Abstract

Adaptive immune cells, such as T cells, integrate information from their extracellular environment through complex signaling networks with exquisite sensitivity in order to direct decisions on proliferation, apoptosis, and cytokine production. These signaling networks are reliant on the interplay between finely tuned secondary messengers, such as Ca

Indexed as

Lab-On-A-Chip DevicesModels, BiologicalBiological ClocksCalciumCalcium SignalingCell SeparationComputer SimulationEquipment DesignFlow Injection AnalysisHumansHydrogen PeroxideJurkat CellsOscillometrySystems IntegrationT-LymphocytesCalciumHydrogen Peroxide

Identifiers

PMID28164205
PMCPMC5360518

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.