Evidence map›Paper›PMID 28164170›Full record

ArticleKidney international reports2016

Ambulatory Blood Pressure in Chronic Kidney Disease: Ready for Prime Time?

Manuel T Velasquez, Srinivasan Beddhu, Ehsan Nobakht, Mahboob Rahman, Dominic S Raj

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 58 citations in OpenAlex.

  1. Blood pressure status, JSH 2019-based control rate, and associated factors among community-dwelling adults: The NOSE study.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  2. Article
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  8. Review
  9. The effects of the atrial natriuretic peptide deficiency on renal cortical mitochondrial bioenergetics in the Dahl SS rat.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  10. Article
  11. Article
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  14. Article
  15. Review
  16. Article
  17. Article
  18. Circadian Control of Sodium and Blood Pressure Regulation.American journal of hypertension · 2021
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Manuel T VelasquezDivision of Renal Diseases and Hypertension, The George Washington University, Washington, DC, USA.
Srinivasan BeddhuUniversity of Utah School of Medicine, Kidney and Liver Clinic, Salt Lake City, Utah, USA.
Ehsan NobakhtDivision of Renal Diseases and Hypertension, The George Washington University, Washington, DC, USA.
Mahboob RahmanUniversity Hospitals Case Medical Center, Department of Medicine-Hypertension, Cleveland, Ohio, USA.
Dominic S RajDivision of Renal Diseases and Hypertension, The George Washington University, Washington, DC, USA.
George Washington University · USUniversity Hospitals Case Medical Center · USUniversity of Utah · US

Funding

SPRINT - Factors Affecting Atherosclerosis Study (FAST)R01DK091437 · NIDDK · UNIVERSITY OF UTAH · PI BEDDHU, SRINIVASAN · 2011 to 2014
$2.3M
Cytokine Gene Polymorphism in CRIC CohortR01DK073665 · NIDDK · UNIVERSITY OF NEW MEXICO · PI RAJ, DOMINIC S · 2006 to 2010
$2.3M
Gut Microbiota and Atherosclerosis in ESRDU01DK099914 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI RAJ, DOMINIC S · 2013 to 2017
$1.9M
Anti-inflammatory Therapy in Diabetic CKDU01DK099924 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI RAJ, DOMINIC S · 2013 to 2018
$1.8M
NIDDK NIH HHS R01 DK073665NIDDK NIH HHS R01 DK091437NIDDK NIH HHS U01 DK099914NIDDK NIH HHS U01 DK099924
6 · The paper itself

Abstract

Hypertension is common in patients with chronic kidney disease (CKD) and is the most important modifiable risk factor for CKD progression and adverse cardiovascular events in these patients. Diagnosis and successful management of hypertension are critically dependent on accurate blood pressure (BP) measurement. This is most relevant to CKD patients, in whom BP control is difficult to achieve and in whom early antihypertensive treatment is imperative to prevent kidney and cardiovascular complications. Accumulated data indicate that ambulatory blood pressure monitoring (ABPM) is better in detecting hypertension than office BP measurement. ABPM is also a superior prognostic marker compared with office BP and has successfully identified hypertensive CKD patients at increased risk. Additionally, ABPM provides information on circadian BP variation and short-term BP variability, which is associated with cardiovascular and renal outcomes. This paper reviews the evidence for the usefulness of ABPM in detection and management of hypertension in CKD patients and discusses our current understanding of the pathophysiology of altered circadian BP rhythm and variability in CKD and the role of abnormal BP patterns detected by ABPM in relation to outcomes in CKD. In addition, this Review examines the emerging role of antihypertensive chronotherapy to tailor BP management to the circadian BP pattern abnormality detected by 24-hour ABPM.

Indexed as

ambulatory blood pressure monitoringcardiovascular diseasechronic kidney diseasecircadian rhythmhypertension

Identifiers

PMID28164170
PMCPMC5283800
OpenAlexW2435519837

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.