Evidence map›Paper›PMID 28164128›Full record

ReviewBioMed research international2017

Roles of miR-17-92 Cluster in Cardiovascular Development and Common Diseases.

Huanyu Gu, Zhuyuan Liu, Lei Zhou

Abstract readReview
In one paragraph

Review in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
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  8. Review
  9. Article
  10. Atherosclerosis: From Molecular Biology to Therapeutic Perspective 3.0.International journal of molecular sciences · 2023
    Article
  11. Role of noncoding RNAs in cardiac ageing.Frontiers in cardiovascular medicine · 2023
    Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Huanyu GuDepartment of Cardiology, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
Zhuyuan LiuDepartment of Cardiology, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
Lei ZhouDepartment of Cardiology, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.ORCID 0000-0002-5985-3177

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs and miRs) are a large class of noncoding, single-stranded, small RNA molecules. The precise control of their expression is essential for keeping tissue homeostasis and normal development of organisms. Thus, unbalanced expression of miRNAs is a hallmark of many diseases. Two to dozens of miRNAs can form into a miRNA cluster, and the miR-17-92 cluster is one of them. Although firstly described as an oncogenic miRNA cluster, the miR-17-92 cluster has also been found to play critical role in normal cardiac development and cardiovascular disease. This review focuses on the characteristics and functions of miR-17-92 cluster in heart.

Indexed as

Multigene FamilyCardiovascular DiseasesCardiovascular SystemHumansMicroRNAsMicroRNAs

Identifiers

PMID28164128
PMCPMC5259667

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.