ArticleAnnals of pediatric endocrinology & metabolism2016
Perinatal factors associated with neonatal thyroid-stimulating hormone in normal newborns.
Article in Annals of pediatric endocrinology & metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 37 citations in OpenAlex.
- An infant with persistent pulmonary hypertension of the newborn and congenital hypothyroidism.Case reports in perinatal medicine · 2026Article
- Association of Certain Maternal and Neonatal Factors with Neonatal Thyroid-Stimulating Hormone Levels: Insights for Congenital Hypothyroidism Prevention.International journal of preventive medicine · 2026Article
- Impact of Maternal and Neonatal Factors on Thyroid-Stimulating Hormone Concentrations in Newborns in Eastern Morocco.Cureus · 2025Article
- Screening for congenital hypothyroidism by using cord blood thyroid stimulating hormone (CBTSH) levels in neonates.Journal of family medicine and primary care · 2025Article
- Neonatal Thyroid-Stimulating Hormone Reference Intervals in Multi-Ethnics Population.Children (Basel, Switzerland) · 2025Article
- Association of pregnancy outcomes with neonatal TSH levels in euthyroid singleton pregnancies.Frontiers in endocrinology · 2025Observational
- Article
- Associations between OGTT results during pregnancy and offspring TSH levels: a birth cohort study.BMC pregnancy and childbirth · 2024Article
- Experiences and Challenges with Congenital Hypothyroidism Newborn Screening in Indonesia: A National Cross-Sectional Survey.International journal of neonatal screening · 2024Article
- Effect of Maternal Triclosan Exposure on Neonatal Thyroid-Stimulating Hormone Levels: A Cross-Sectional Study.Journal of environmental and public health · 2022Article
- Transient Hyperintensity of the Infant Thyroid Gland on T1-Weighted MR Imaging: Correlation with Postnatal Age, Gestational Age, and Signal Intensity of the Pituitary Gland.AJNR. American journal of neuroradiology · 2021Article
- The role of placental iodine storage in the neonatal thyroid stimulating hormone surge: iodine as a driving force to adapt the terrestrial life.Journal of endocrinological investigation · 2021Article
- A Detailed Analysis of the Factors Influencing Neonatal TSH: Results From a 6-Year Congenital Hypothyroidism Screening Program.Frontiers in endocrinology · 2020Article
- Comparison of iodine status pre- and post-mandatory iodine fortification of bread in South Australia: a population study using newborn thyroid-stimulating hormone concentration as a marker.Public health nutrition · 2019Article
- Newborn Screening for Selected Disorders in Nepal: A Pilot Study.International journal of neonatal screening · 2019Article
- CONGENITAL HYPOTHYROIDISM SCREENING RESULTS IN THE TURKISH PROVINCE OF ADIYAMAN IN 2015-2020.Acta endocrinologica (Bucharest, Romania : 2005)Article
- Recall Rate in Congenital Hypothyroidism Screening: Influence of the Day of Sample Collection and Lower Cutoff.Acta endocrinologica (Bucharest, Romania : 2005)Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study was to evaluate the effect of neonatal, maternal, and delivery factors on neonatal thyroid-stimulating hormone (TSH) of healthy newborns.
methodsMedical records of 705 healthy infants born through normal vaginal delivery were reviewed. Neonatal TSH levels obtained by neonatal screening tests were analyzed in relation to perinatal factors and any associations with free thyroxine (FT4) and 17-α hydroxyprogesterone (17OHP) levels.
resultsAn inverse relationship was found between TSH and sampling time after birth. Twin babies and neonates born by vacuum-assisted delivery had higher TSH levels than controls. First babies had higher TSH levels than subsequent babies. Birth weight, gestational age, maternal age and duration from the rupture of the membrane to birth were not related to neonatal TSH. There were no significant differences in TSH level according to sex, Apgar scores, labor induction, the presence of maternal disease and maternal medications. There was a positive association between TSH and 17OHP level but not between TSH and FT4 level. Multiple linear regression analyses showed that sampling time, mode of delivery, birth order, and 17OHP level were significant factors affecting neonatal TSH level.
conclusionNeonatal TSH levels of healthy normal newborns are related with multiple factors. Acute stress during delivery may influence the neonatal TSH level in early neonatal period.
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