Evidence map›Paper›PMID 28164069›Full record

ArticleClinical and translational imaging2014

Multimodality molecular imaging of the lung.

Delphine L Chen, Paul E Kinahan

Open access · bronzeAbstract read
In one paragraph

Article in Clinical and translational imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Morphology supporting function: attenuation correction for SPECT/CT, PET/CT, and PET/MR imaging.The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Delphine L ChenDepartment of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA. Division of Radiological Sciences and Nuclear Medicine, Mallinckrodt Institute of Radiology, Campus Box 8225, 510 S. Kingshighway Blvd, St. Louis, MO 63110, USA.
Paul E KinahanDepartment of Radiology and Bioengineering and Physics, University of Washington Medical Center, Seattle, WA, USA.
University of Washington Medical Center · USWashington University in St. Louis · US

Funding

Advanced PET/CT Imaging for Improving Clinical TrialsU01CA148131 · NCI · UNIVERSITY OF WASHINGTON · PI KINAHAN, PAUL E., LINDEN, HANNAH M · 2010 to 2019
$6.0M
Enabling Ultra Low Dose PET/CT ImagingR01CA160253 · NCI · UNIVERSITY OF WASHINGTON · PI KINAHAN, PAUL E. · 2011 to 2015
$3.5M
POSITRON EMISSION TOMOGRAPHIC IMAGING OF LUNG TRANSPLANTR01HL121218 · NHLBI · WASHINGTON UNIVERSITY · PI CHEN, DELPHINE L, GELMAN, ANDREW ERIC · 2014 to 2017
$2.8M
IMAGING MACROPHAGE ACTIVATION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASER01HL116389 · NHLBI · WASHINGTON UNIVERSITY · PI CHEN, DELPHINE L · 2012 to 2014
$1.1M
NCI NIH HHS R01 CA160253NCI NIH HHS U01 CA148131NHLBI NIH HHS R01 HL116389NHLBI NIH HHS R01 HL121218
6 · The paper itself

Abstract

Lung diseases cause significant morbidity and mortality and lead to high healthcare utilization. However, few lung disease-specific biomarkers are available to accurately monitor disease activity for the purposes of clinical management or drug development. Advances in cross-modal imaging technologies, such as combined positron emission tomography (PET) and magnetic resonance (MR) imaging scanners and PET or single-photon emission computed tomography (SPECT) combined with computed tomography (CT), may aid in the development of noninvasive, molecular-based biomarkers for lung disease. However, the lungs pose particular challenges in obtaining accurate quantification of imaging data due to the low density of the organ and breathing motion. This review covers the basic physics underlying PET, SPECT, CT, and MR lung imaging and presents technical considerations for multimodal imaging with regard to PET and SPECT quantification. It also includes a brief review of the current and potential clinical applications for these hybrid imaging technologies.

Indexed as

Lung cancerLung diseaseMagnetic resonance imagingMolecular imagingMultimodality imagingPositron emission tomographySingle photon emission computed tomography

Identifiers

PMID28164069
PMCPMC5289702
OpenAlexW2083268881

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.