Evidence map›Paper›PMID 28164040›Full record

ArticleFrontiers in cellular and infection microbiology2017

TLR2

Débora de Fátima Almeida, Thais F de Campos Fraga-Silva, Amanda R Santos, Angela C Finato, Camila M Marchetti, Marjorie de Assis Golim, Vanessa S Lara, Maria S P Arruda, James Venturini

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. TLR2Frontiers in immunology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Débora de Fátima AlmeidaLaboratory of Experimental Immunopathology, Department of Chemistry, Universidade Estadual Paulista Bauru, Brazil.
Thais F de Campos Fraga-SilvaLaboratory of Experimental Immunopathology, Department of Chemistry, Universidade Estadual PaulistaBauru, Brazil; Department of Microbiology and Immunology, Institute of Biosciences of Botucatu, Universidade Estadual PaulistaBotucatu, Brazil.
Amanda R SantosLaboratory of Experimental Immunopathology, Department of Chemistry, Universidade Estadual Paulista Bauru, Brazil.
Angela C FinatoLaboratory of Experimental Immunopathology, Department of Chemistry, Universidade Estadual Paulista Bauru, Brazil.
Camila M MarchettiLaboratory of Experimental Immunopathology, Department of Chemistry, Universidade Estadual Paulista Bauru, Brazil.
Marjorie de Assis GolimBotucatu Blood Center, Universidade Estadual Paulista Botucatu, Brazil.
Vanessa S LaraDepartment of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of São Paulo Bauru, Brazil.
Maria S P ArrudaLaboratory of Experimental Immunopathology, Department of Chemistry, Universidade Estadual Paulista Bauru, Brazil.
James VenturiniLaboratory of Experimental Immunopathology, Department of Chemistry, Universidade Estadual Paulista Bauru, Brazil.
Universidade Estadual Paulista (Unesp) · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dermatophytosis is one of the most common human infections affecting both immunocompetent individuals and immunocompromised patients, in whom the disease is more aggressive and can reach deep tissues. Over the last decades, cases of deep dermatophytosis have increased and the dermatophyte-host interplay remains poorly investigated. Pattern recognition molecules, such as Toll-like receptors (TLR), play a crucial role against infectious diseases. However, there has been very little research reported on dermatophytosis. In the present study, we investigated the role of TLR2 during the development of experimental deep dermatophytosis in normal mice and mice with alloxan-induced diabetes mellitus, an experimental model of diabetes that exhibits a delay in the clearance of the dermatophyte,

Indexed as

Diabetes ComplicationsAnimalsColony Count, MicrobialCytokinesDisease Models, AnimalMacrophagesMice, Inbred C57BLMice, KnockoutTineaT-Lymphocytes, RegulatoryToll-Like Receptor 2TrichophytonCytokinesTlr2 protein, mouseToll-Like Receptor 2deep dermatophytosishypoinsulinemia-hyperglycemiamonocytestoll-like receptorsTrichophyton mentagrophytes

Identifiers

PMID28164040
PMCPMC5248405
OpenAlexW2579696844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.