ArticleElectronic physician2016
The Relationship Between Blood Lead Level and Preeclampsia.
Article in Electronic physician, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Prenatal lead exposure and risk of Pregnancy-Induced hypertension: A systematic review and Meta-Analysis.BMC pregnancy and childbirth · 2025Pooled it
- A global perspective of correlation between maternal blood lead levels and risks of preeclampsia: An updated systematic review and meta-analysis.Frontiers in public health · 2022Pooled it
- Article
- Lead exposure across early life in Latin America and the Caribbean: prevention strategies and reproductive health considerations.Frontiers in reproductive health · 2026Review
- Trends of Blood Lead Levels in US Pregnant Women: The National Health and Nutrition Examination Survey (2001-2018).Frontiers in public health · 2022Article
- Lead Levels in Non-Occupationally Exposed Women with Preeclampsia.Molecules (Basel, Switzerland) · 2021Article
- Blood lead level monitoring related to environmental exposure in the general Iranian population: a systematic review and meta-analysis.Environmental science and pollution research international · 2021Review
- Blood lead levels in antenatal women and its association with iron deficiency anemia and adverse pregnancy outcomes.Journal of family medicine and primary care · 2020Article
- Environmental Toxicant Exposure and Hypertensive Disorders of Pregnancy: Recent Findings.Current hypertension reports · 2018Review
- Blood Lead Levels in Women of Child-Bearing Age in Sub-Saharan Africa: A Systematic Review.Frontiers in public health · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLead is a heavy metal to which people are commonly exposed. One of the possible mechanisms of tissue damages caused by this toxic metal is oxidative stress, which in turn may cause numerous pregnancy complications such as preeclampsia. The present study was conducted to determine the relationship between maternal Blood Lead Level (BLL) and preeclampsia.
methodsThe present case-control study was conducted on 158 pregnant women admitted to a hospital in Zanjan, Iran, from August 2015 to March 2016. To measure their BLL, 1.5 cc of blood was drawn from each participant. The demographic and obstetric details of the patients were recorded in a form. The potentiometric method was used to test the samples. The data obtained were analyzed by SPSS version 22, using Mann-Whitney U test, the Chi square, independent-samples t-test, Pearson product-moment correlation, and simple linear regression analysis.
resultsThe mean BLL was 6.24±1.74 μg/dl in the control group and 8.04±3.4 μg/dl in the preeclampsia group. The two groups were matching in terms of the mother's age and education and the household income. A significant relationship was observed between BLL and preeclampsia (p=0.028), as per every unit of increase (1 μg/dl) in BLL, systolic blood pressure increased by 0.014 mm Hg and diastolic blood pressure by 0.013 mm Hg (p=0.004).
conclusionThe results obtained suggest a relationship between BLL and preeclampsia. Global health measures should be taken to remove the exposure to lead so as to reduce its absorption by pregnant women.
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Registered trials
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