Evidence map›Paper›PMID 28163816›Full record

ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada

Plasmacytoid urothelial carcinoma (PUC): Imaging features with histopathological correlation.

Andrew D Chung, Nicola Schieda, Trevor A Flood, Ilias Cagiannos, Kien T Mai, Shawn Malone, Christopher Morash, Shaheed W Hakim, Rodney H Breau

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Evaluating biparametric MRI for diagnosing muscle-invasive bladder cancer with variant urothelial histology: a multicenter study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  7. Review
  8. Article
  9. Plasmacytoid bladder cancer: a rare case report.Annals of medicine and surgery (2012) · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Andrew D ChungDepartment of Medical Imaging; The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Nicola SchiedaDepartment of Medical Imaging; The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Trevor A FloodDepartment of Anatomical Pathology; The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Ilias CagiannosDepartment of Surgery, Division of Urology; The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Kien T MaiDepartment of Anatomical Pathology; The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Shawn MaloneDepartment of Radiation Oncology; The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Christopher MorashDepartment of Surgery, Division of Urology; The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Shaheed W HakimDepartment of Anatomical Pathology; The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Rodney H BreauDepartment of Surgery, Division of Urology; The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
University of Ottawa · CAOttawa Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPlasmacytoid urothelial carcinoma (PUC) is a high-grade variant of conventional urothelial cell carcinoma. This study is the first to describe the imaging findings of PUC, which are previously unreported, using clinical and histopathological correlation.

methodsWith internal review board approval, we identified 22 consecutive patients with PUC from 2007-2014. Clinical parameters, including age, gender, therapy, surgical margins, and long-term outcome, were recorded. Baseline imaging was reviewed by an abdominal radiologist who evaluated for tumour detectability/location/morphology, local staging, and presence/location of metastases. Pelvic peritoneal spread of tumour (defined as >5mm thick soft tissue spreading along fascial planes) was also evaluated. Followup imaging was reviewed for presence of local recurrence or metastases.

resultsMedian age at presentation was 74 years (range 51-86), with only three female patients. Imaging features of the primary tumour in this study were not unique for PUC. Muscle-invasive disease was present on pathology in 19/22 (86%) of tumours, with distant metastases in 2/22 (9%) at baseline imaging. Pelvic peritoneal spread of tumour was radiologically present in 4/20 (20%) at baseline. During followup, recurrent/residual tumour was documented in 16/22 (73%) patients and 7/16 (44%) patients eventually developed distant metastases. Median time to disease recurrence in patients who underwent curative surgery was three months (range 0-19).

conclusionsPUC is an aggressive variant of urothelial carcinoma with poor prognosis. Pelvic peritoneal spread of tumour as thick sheets extending along fascial planes may represent a characteristic imaging finding of locally advanced PUC.

Identifiers

PMID28163816
PMCPMC5262514
OpenAlexW2573900640

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.