Evidence map›Paper›PMID 28163745›Full record

ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2016

Comparison of short-term efficacy of iron sucrose with those of ferric chloride in hemodialysis patients: An open-label study.

Po-Jen Hsiao, Jenq-Shyong Chan, Kun-Lin Wu, Wen-Fang Chiang, Jing-Shu Huang, Chia-Chao Wu, Pauling Chu, Jin-Shuen Chen

Abstract read
In one paragraph

Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Intravenous iron therapy for non-anaemic, iron-deficient adults.The Cochrane database of systematic reviews · 2019
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Po-Jen HsiaoDepartment of Medicine, Division of Nephrology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Republic of China; Department of Internal Medicine, Division of Nephrology, Taoyuan Armed Forces General Hospital, Taiwan, Republic of China.
Jenq-Shyong ChanDepartment of Internal Medicine, Division of Nephrology, Taoyuan Armed Forces General Hospital, Taiwan, Republic of China.
Kun-Lin WuDepartment of Medicine, Division of Nephrology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Republic of China; Department of Internal Medicine, Division of Nephrology, Taoyuan Armed Forces General Hospital, Taiwan, Republic of China.
Wen-Fang ChiangDepartment of Medicine, Division of Nephrology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Republic of China; Department of Internal Medicine, Division of Nephrology, Taoyuan Armed Forces General Hospital, Taiwan, Republic of China.
Jing-Shu HuangDepartment of Medicine, Division of Nephrology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Republic of China.
Chia-Chao WuDepartment of Medicine, Division of Nephrology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Republic of China.
Pauling ChuDepartment of Medicine, Division of Nephrology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Republic of China.
Jin-Shuen ChenDepartment of Medicine, Division of Nephrology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is intriguing and imperative that the comparison of the iron preparations in hemodialysis (HD) patients. This study aimed to observe the short-term efficacy of parenteral iron sucrose and ferric chloride in HD patients. MATERIALS AND

methodsThis was a consecutive 10-week single-blind study in Taiwan. An intravenous iron supplement of 100 mg/week was administered as an infusion in 100 ml of normal saline, until a total dose of 1000 mg was achieved. The primary outcome was evaluated by the changes in serum hematocrit (Hct) levels. The changes in serum Hct and iron indices were evaluated every 2 weeks for 10 weeks. The results were collected from 21 April to 4 July 2013.

resultsA total of 56 HD patients completed the study. Subjects were randomized into an iron sucrose group (26 patients) and a ferric chloride group (30 patients). Between the two treatment groups, there were no statistically significant differences in the change in serum Hct, ferritin, iron, or total iron binding capacity (

conclusionIn the study subjects, parenteral iron sucrose was as effective and safe as ferric chloride for treating anemia in HD patients.

Indexed as

Anemiaferric chloridehemodialysisintravenous ironiron sucrose

Identifiers

PMID28163745
PMCPMC5244645

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.