Evidence map›Paper›PMID 28163680›Full record

ArticleFrontiers in neuroinformatics2017

SEGMA: An Automatic SEGMentation Approach for Human Brain MRI Using Sliding Window and Random Forests.

Ahmed Serag, Alastair G Wilkinson, Emma J Telford, Rozalia Pataky, Sarah A Sparrow, Devasuda Anblagan, Gillian Macnaught, Scott I Semple, James P Boardman

Abstract read
In one paragraph

Article in Frontiers in neuroinformatics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ahmed SeragMRC Centre for Reproductive Health, University of Edinburgh Edinburgh, UK.
Alastair G WilkinsonDepartment of Radiology, Royal Hospital for Sick Children Edinburgh, UK.
Emma J TelfordMRC Centre for Reproductive Health, University of Edinburgh Edinburgh, UK.
Rozalia PatakyMRC Centre for Reproductive Health, University of Edinburgh Edinburgh, UK.
Sarah A SparrowMRC Centre for Reproductive Health, University of Edinburgh Edinburgh, UK.
Devasuda AnblaganMRC Centre for Reproductive Health, University of EdinburghEdinburgh, UK; Centre for Clinical Brain Sciences, University of EdinburghEdinburgh, UK.
Gillian MacnaughtClinical Research Imaging Centre, University of Edinburgh Edinburgh, UK.
Scott I SempleClinical Research Imaging Centre, University of EdinburghEdinburgh, UK; Centre for Cardiovascular Science, University of EdinburghEdinburgh, UK.
James P BoardmanMRC Centre for Reproductive Health, University of EdinburghEdinburgh, UK; Centre for Clinical Brain Sciences, University of EdinburghEdinburgh, UK.

Funding

Medical Research Council G0701127Medical Research Council MR/K026992/1Medical Research Council MR/N022556/1
6 · The paper itself

Abstract

Quantitative volumes from brain magnetic resonance imaging (MRI) acquired across the life course may be useful for investigating long term effects of risk and resilience factors for brain development and healthy aging, and for understanding early life determinants of adult brain structure. Therefore, there is an increasing need for automated segmentation tools that can be applied to images acquired at different life stages. We developed an automatic segmentation method for human brain MRI, where a sliding window approach and a multi-class random forest classifier were applied to high-dimensional feature vectors for accurate segmentation. The method performed well on brain MRI data acquired from 179 individuals, analyzed in three age groups: newborns (38-42 weeks gestational age), children and adolescents (4-17 years) and adults (35-71 years). As the method can learn from partially labeled datasets, it can be used to segment large-scale datasets efficiently. It could also be applied to different populations and imaging modalities across the life course.

Indexed as

brainclassificationlarge-scalelife-courseMRIrandom forestssliding windowtissue segmentation

Identifiers

PMID28163680
PMCPMC5247463

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.