Evidence map›Paper›PMID 28163538›Full record

ArticleJournal of pharmacology & pharmacotherapeutics

Comparison of efficacy, safety, and cost-effectiveness of rupatadine and olopatadine in patients of allergic rhinitis: A prospective, randomized, double-blind, parallel group study.

Ganesh Dakhale, Yogesh Tathod, Seema Patel, Sonali Pimpalkhute, Latesh Raghute, Ajita Khamkar

Open access · hybridAbstract read
In one paragraph

Article in Journal of pharmacology & pharmacotherapeutics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ganesh DakhaleDepartment of Pharmacology, Government Medical College, Nagpur, Maharashtra, India.
Yogesh TathodDepartment of Pharmacology, Government Medical College, Nagpur, Maharashtra, India.
Seema PatelDepartment of ENT, Government Medical College, Nagpur, Maharashtra, India.
Sonali PimpalkhuteDepartment of Pharmacology, Government Medical College, Nagpur, Maharashtra, India.
Latesh RaghuteDepartment of Pharmacology, Government Medical College, Nagpur, Maharashtra, India.
Ajita KhamkarDepartment of Pharmacology, Government Medical College, Nagpur, Maharashtra, India.
Government Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the efficacy, safety, and cost-effectiveness of rupatadine and olopatadine in patients of allergic rhinitis (AR). MATERIALS AND

methodsA 2-week, single-centered, randomized, double-blind, parallel group comparative clinical study was conducted on patients with AR. Following inclusion and exclusion criteria, 67 patients were recruited and randomized to two treatment groups and received the respective drugs for 2 weeks. At follow-up, parameters assessed were total nasal symptom score (TNSS), change in total and differential count of eosinophil.

resultsIn olopatadine group, there was a significantly higher reduction in TNSS (

conclusionOlopatadine is a better choice in AR in comparison to rupatadine due to its better efficacy and safety profile.

Indexed as

Absolute eosinophil countatopic disordersTNSS

Identifiers

PMID28163538
PMCPMC5242030
OpenAlexW2566447102

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.