Evidence map›Paper›PMID 28163307›Full record

ReviewNature reviews. Nephrology2017

Role of NAD

Kathleen A Hershberger, Angelical S Martin, Matthew D Hirschey

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 132 papers.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 217 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Nicotinamide Attenuates Complement and Coagulation Pathways and Resultant Renal Fibrosis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  10. NADNature biomedical engineering · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Metabolic dysregulation in the heart in obesity-associated HFpEF.Frontiers in cardiovascular medicine · 2025
    Article
  19. Review
  20. Review

72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kathleen A HershbergerDuke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, 300 N Duke Street, Durham, North Carolina 27701, USA.
Angelical S MartinDuke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, 300 N Duke Street, Durham, North Carolina 27701, USA.
Matthew D HirscheyDuke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, 300 N Duke Street, Durham, North Carolina 27701, USA.
Duke University · US

Funding

Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Sarah B. Peskoe · 2006 to 2026
$24.6M
ORGANIZATION AND FUNCTIONS OF CELLULAR STRUCTUREST32GM007184 · NIGMS · DUKE UNIVERSITY · PI JINKS-ROBERTSON, SUE · 1985 to 2019
$18.2M
Pharmacological Sciences Training ProgramT32GM007105 · NIGMS · DUKE UNIVERSITY · PI KUHN, CYNTHIA M · 1985 to 2019
$9.0M
Renal Genomics CoreP30DK096493 · NIDDK · DUKE UNIVERSITY · PI PATEL, UPTAL D · 2012 to 2016
$5.9M
Studies on the Mechanisms by which SIRT5 Regulates Aging and DiseaseR01AG045351 · NIA · DUKE UNIVERSITY · PI HIRSCHEY, MATTHEW D · 2014 to 2023
$4.4M
Ethanol-induced Protein Acylation Regulates MetabolismR01AA022146 · NIAAA · DUKE UNIVERSITY · PI FRITZ, KRISTOFER S, HIRSCHEY, MATTHEW D · 2013 to 2017
$2.3M
The Role of Acetylation in the Regulation Iron-Sulfur Cluster Biogenesis and MitoF31HL123275 · NHLBI · DUKE UNIVERSITY · PI MARTIN, ANGELICAL S. · 2014 to 2016
$98k
The Role of SIRT5 in Regulating Cardiac Function and MetabolismF31HL127959 · NHLBI · DUKE UNIVERSITY · PI HERSHBERGER, KATHLEEN ANNE · 2015 to 2017
$73k
NHLBI NIH HHS F31 HL123275NHLBI NIH HHS F31 HL127959NIAAA NIH HHS R01 AA022146NIA NIH HHS P30 AG028716NIA NIH HHS R01 AG045351NIDDK NIH HHS P30 DK096493NIGMS NIH HHS T32 GM007105NIGMS NIH HHS T32 GM007184
6 · The paper itself

Abstract

The coenzyme nicotinamide adenine dinucleotide (NAD

Indexed as

AnimalsDisease Models, AnimalHeartHeart DiseasesHumansKidneyKidney DiseasesMitochondriaNADOxidation-ReductionSignal TransductionSirtuinsNADSirtuins

Identifiers

PMID28163307
PMCPMC5508210
OpenAlexW2586109823

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.