Evidence map›Paper›PMID 28162773›Full record

ReviewTrends in biotechnology2017

Enabling Microfluidics: from Clean Rooms to Makerspaces.

David I Walsh, David S Kong, Shashi K Murthy, Peter A Carr

Open access · bronzeAbstract readReview
In one paragraph

Review in Trends in biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 171 citations in OpenAlex.

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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

David I WalshMassachusetts Institute of Technology Lincoln Laboratory, Massachusetts Institute of Technology, Lexington, MA, USA. Electronic address: david.walsh@ll.mit.edu.
David S KongMassachusetts Institute of Technology Lincoln Laboratory, Massachusetts Institute of Technology, Lexington, MA, USA.
Shashi K MurthyDepartment of Chemical Engineering, Northeastern University, Boston, MA, USA; Barnett Institute of Chemical and Biological Analysis, Northeastern University, Boston, MA, USA.
Peter A CarrMassachusetts Institute of Technology Lincoln Laboratory, Massachusetts Institute of Technology, Lexington, MA, USA. Electronic address: carr@ll.mit.edu.
Massachusetts Institute of Technology · USMIT Lincoln Laboratory · USNortheastern University · US

Funding

MIT Center for Integrative Synthetic BiologyP50GM098792 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI WEISS, RON · 2013 to 2017
$11.0M
ANIMAL HUSBANDRY SUPPORT SERVICES FOR NIEHS27304C0002 · NIEHS · 2007 to 2008
$5.0M
Genetic circuits for high-throughput, multi-sensory, live cell microRNA profR01CA173712 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI WEISS, RON · 2013 to 2017
$2.5M
Role of Mitochondrial CYP2E1 in Chemical Exposure-Driven NeurodegenerationF32ES027306 · NIEHS · DUKE UNIVERSITY · PI HARTMAN, JESSICA HELENE · 2016 to 2018
$171k
Investigation of metabolites related to manganese exposureF31ES027304 · NIEHS · UNIVERSITY OF WASHINGTON · PI BAKER, MARISSA GAYL · 2016 to 2017
$61k
NCI NIH HHS R01 CA173712NIEHS NIH HHS 27304C0002NIEHS NIH HHS 27306C0002NIGMS NIH HHS P50 GM098792
6 · The paper itself

Abstract

The traditional requirement for clean rooms and specialized skills has inhibited many biologists from pursuing new microfluidic innovations. Makerspaces provide a growing alternative to clean rooms: they provide low-cost access to fabrication equipment such as laser cutters, plotter cutters, and 3D printers; use commercially available materials; and attract a diverse community of product designers. This Opinion discusses the materials, tools, and building methodologies particularly suited for developing novel microfluidic devices in these spaces, with insight into biological applications and leveraging the maker community. The lower barrier to access of makerspaces ameliorates the otherwise poor accessibility and scalability of microfluidic prototyping.

Indexed as

Environment, ControlledBiotechnologyEquipment DesignEquipment Failure AnalysisFacility Design and ConstructionMicrofluidics

Identifiers

PMID28162773
PMCPMC6812491
OpenAlexW2585582807

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.