Evidence map›Paper›PMID 28161838›Full record

ReviewInternational urology and nephrology2017

Anticoagulant-related nephropathy: a case report and review of the literature of an increasingly recognized entity.

Rigas G Kalaitzidis, Anila Duni, Georgios Liapis, Olga Balafa, Sofia Xiromeriti, Paulos Karolos Rapsomanikis, Moses S Elisaf

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in International urology and nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  9. Review
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  12. Article
  13. Anticoagulant-Related Nephropathy.Journal of the American Society of Nephrology : JASN · 2018
    Review
  14. Article
  15. Article
  16. Anticoagulant-related nephropathy: a pathological note.Journal of thrombosis and thrombolysis · 2018
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rigas G KalaitzidisDepartment of Nephrology, University Hospital of Ioannina, Ioannina, Greece. rigaska@gmail.com.
Anila DuniDepartment of Nephrology, University Hospital of Ioannina, Ioannina, Greece.
Georgios Liapis1st Department of Pathology Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Olga BalafaDepartment of Nephrology, University Hospital of Ioannina, Ioannina, Greece.
Sofia XiromeritiDepartment of Nephrology, University Hospital of Ioannina, Ioannina, Greece.
Paulos Karolos RapsomanikisDepartment of Nephrology, University Hospital of Ioannina, Ioannina, Greece.
Moses S ElisafDepartment of Nephrology, University Hospital of Ioannina, Ioannina, Greece.
University Hospital of Ioannina · GRNational and Kapodistrian University of Athens · GRUniversity of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment with oral anticoagulants has been associated with worsening kidney function in patients with chronic kidney disease (CKD) as well as among patients without underlying CKD. Thus, anticoagulant-related nephropathy (ARN) is an increasingly recognized entity nowadays, mainly associated with warfarin anticoagulation. Recent evidence indicates that patients treated with the direct anticoagulants may also be at risk of ARN. However, the true incidence of anticoagulant-related nephropathy is difficult to determine. The typical histological lesion involves renal tubular occlusion by red blood cells (RBCs), tubular red blood cell casts on light microscopy and dysmorphic RBCs in the glomerulus on electron microscopy. In the absence of active glomerulonephritis or other inflammatory changes that could account for glomerular hemorrhage, the above findings confirm the diagnosis. Dabigatran etexilate was the first direct oral anticoagulant approved for stroke prevention in patients with non-valvular atrial fibrillation. In this article, we describe a rare case of dabigatran etexilate-induced nephropathy in a patient with preexisting IgA nephropathy and review the recent literature regarding this increasingly recognized entity.

Indexed as

Acute Kidney InjuryAgedAnticoagulantsDabigatranFemaleGlomerulonephritis, IGAHematuriaHumansRenal Insufficiency, ChronicRisk FactorsAnticoagulantsDabigatranAnticoagulant-related nephropathyDabigatran etexilateIgA nephropathyOral anticoagulantsWarfarin

Identifiers

PMID28161838
OpenAlexW2583356829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.