Observational studyGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2017
Peripapillary retinal vessel density in eyes with acute primary angle closure: an optical coherence tomography angiography study.
Observational study in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Vessel Density and Structural Measurements in Primary Angle-Closure Suspect Glaucoma Using Optical Coherence Tomography Angiography.BioMed research international · 2020Trial
- Longitudinal changes in vessel density and retinal nerve fiber layer thickness after acute primary angle closure.BMC ophthalmology · 2026Article
- Long-term optic nerve head microvascular impairment after acute primary angle closure: an OCTA study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Alterations in Retinal Vasculometry After Acute Primary Angle Closure Episode: A Comparative Analysis.Translational vision science & technology · 2026Article
- Comparing structural and vascular parameters between healthy eyes and eyes with primary angle-closure disease.BMC ophthalmology · 2026Article
- A Method for Peripapillary Retinal Vessel Tortuosity Measurement and Its Clinical Correspondence.Translational vision science & technology · 2025Article
- Comparison between open-angle glaucoma and angle-closure glaucoma regarding the short-term optic disc vessel density changes after trabeculectomy.Lasers in medical science · 2023Article
- Parapapillary choroidal microvascular density in acute primary angle-closure and primary open-angle glaucoma: an optical coherence tomography angiography study.The British journal of ophthalmology · 2023Observational
- An Analysis of Optical Coherence Tomography Angiography (OCT-A) Perfusion Density Maps in Patients Treated for Retinal Vein Occlusion with Intravitreal Aflibercept.Diagnostics (Basel, Switzerland) · 2023Article
- The Association between Vascular Abnormalities and Glaucoma-What Comes First?International journal of molecular sciences · 2023Review
- Changes of macular blood flow and structure in acute primary angle closure glaucoma.International ophthalmology · 2022Article
- Quantification of Iris Atrophy by Swept-Source Optical Coherence Tomography in Posner-Schlossman Syndrome.Journal of clinical medicine · 2022Article
- Intraocular Pressure-Induced Endothelial Dysfunction of Retinal Blood Vessels Is Persistent, but Does Not Trigger Retinal Ganglion Cell Loss.Antioxidants (Basel, Switzerland) · 2022Article
- Optical coherence tomography angiography of the macular microcirculation in acute primary angle closure treated with phacoemulsification.International ophthalmology · 2022Article
- Spatial positional relationship between macular superficial vessel density and ganglion cell-inner plexiform layer thickness in primary angle closure glaucoma.International ophthalmology · 2022Article
- Peripapillary changes after vitrectomy and silicone oil tamponade for rhegmatogenous retinal detachment.Indian journal of ophthalmology · 2021Article
- Peripapillary vessel density measurement of quadrant and clock-hour sectors in primary angle closure glaucoma using optical coherence tomography angiography.BMC ophthalmology · 2021Article
- Changes in circumpapillary retinal vessel density after acute primary angle closure episode via OCT angiography.International ophthalmology · 2021Article
- HSP70 expression before and after treatment and its clinical value in patients with acute angle-closure glaucoma.Experimental and therapeutic medicine · 2021Article
- Macular vessel density and foveal avascular zone parameters in patients after acute primary angle closure determined by OCT angiography.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose was to investigate peripapillary retinal vessel density in resolved acute primary angle closure (APAC) eyes.
methodsThis was a prospective, cross-sectional observational study. Thirty-four eyes of 34 patients with unilateral APAC were included, together with the fellow eyes with primary angle closure suspect (PACS) as controls. Peripapillary retinal vessel density was measured using optical coherence tomography (OCT) angiography. Peripapillary retinal vessel density was compared in both eyes and the potential relationship with visual field (VF) test results was evaluated.
resultsAfter an acute attack, the peripapillary retinal vessel density was lower in the APAC than in the PACS eyes (79.3 ± 8.2 versus 85.6 ± 4.9, respectively; P = 0.001). The VF mean deviation (MD) (-7.7 ± 6.7 versus -3.3 ± 1.8 dB, P = 0.002), and the pattern standard deviation (PSD) (4.6 ± 3.3 versus 2.4 ± 0.9 dB, P = 0.001) were worse for the APAC than the PACS eyes, but both had similar thicknesses of the retinal nerve fiber layer (RNFL) (111.8 ± 9.6 versus 114.1 ± 29.1 μm, P = 0.880) and ganglion cell complex (GCC) (94.7 ± 7.5 versus 91.8 ± 9.3 μm, P = 0.328). The peripapillary retinal vessel density was significantly correlated with the VF MD (vessel density: r = 0.455, P = 0.008) and PSD (vessel density: r = -0.592, P < 0.001) in the APAC eyes.
conclusionsEven when IOP was normalized after the acute attack, the APAC eyes had a lower peripapillary retinal vessel density, which was correlated with the VF values. OCT angiography is a reliable method for detecting vascular changes in glaucomatous eyes that show no thinning of the RNFL and GCC.
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