Evidence map›Paper›PMID 28161798›Full record

ArticleAmino acids2017

Behavioral and inflammatory response in animals exposed to a low-pressure blast wave and supplemented with β-alanine.

Jay R Hoffman, Amitai Zuckerman, Omri Ram, Oren Sadot, Jeffrey R Stout, Ishay Ostfeld, Hagit Cohen

Open access · hybridAbstract read
In one paragraph

Article in Amino acids, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  7. Article
  8. Review
  9. A multi-staged neuropeptide response to traumatic brain injury.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jay R HoffmanInstitute of Exercise Physiology and Wellness, Sport and Exercise Science, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, 32816, USA. jay.hoffman@ucf.edu.
Amitai ZuckermanDivision of Psychiatry, Anxiety and Stress Research Unit, Faculty of Health Sciences, Beer-Sheva Mental Health Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Omri RamDepartment of Mechanical Engineering, Ben-Gurion University, Beer-Sheva, Israel.
Oren SadotDepartment of Mechanical Engineering, Ben-Gurion University, Beer-Sheva, Israel.
Jeffrey R StoutInstitute of Exercise Physiology and Wellness, Sport and Exercise Science, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, 32816, USA.
Ishay OstfeldIsrael Defense Forces, Medical Corps, Tel Aviv, Israel.
Hagit CohenDivision of Psychiatry, Anxiety and Stress Research Unit, Faculty of Health Sciences, Beer-Sheva Mental Health Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Ben-Gurion University of the Negev · ILUniversity of Central Florida · USIsrael Defense Forces Medical Corps · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the benefit of β-alanine (BA) supplementation on behavioral and cognitive responses relating to mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD) in rats exposed to a low-pressure blast wave. Animals were fed a normal diet with or without (PL) BA supplementation (100 mg kg

Indexed as

Dietary SupplementsAnimalsbeta-AlanineBlast InjuriesBrain ChemistryBrain-Derived Neurotrophic FactorBrain InjuriesCarnosineGene ExpressionGlial Fibrillary Acidic ProteinHistidineMaleNeuropeptide YRatsRats, Sprague-DawleyStress Disorders, Post-Traumaticbeta-AlanineBrain-Derived Neurotrophic FactorCarnosineGfap protein, ratGlial Fibrillary Acidic ProteinHistidineMapt protein, ratNeuropeptide Ytau ProteinsBDNFCarnosineGFAPMild traumatic brain injurySupplementation

Identifiers

PMID28161798
PMCPMC5383715
OpenAlexW2584108237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.