Evidence map›Paper›PMID 28161785›Full record

ArticleJournal of molecular modeling2017

New biochemical insight of conserved water molecules at catalytic and structural Zn

Bornali Chakrabarti, Hridoy R Bairagya, Bishnu P Mukhopadhyay, K Sekar

Abstract read
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Article in Journal of molecular modeling, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Bornali ChakrabartiDepartment of Chemistry, National Institute of Technology-Durgapur, Durgapur, 713209, India.
Hridoy R BairagyaDepartment of Chemistry, National Institute of Technology-Durgapur, Durgapur, 713209, India.
Bishnu P MukhopadhyayDepartment of Chemistry, National Institute of Technology-Durgapur, Durgapur, 713209, India. bpmk2@yahoo.com.
K SekarDepartment of Computational and Data Sciences Indian Institute of Science, Laboratory for Structural Biology and Bio-computing, Bangalore, 560 012, India.
National Institute of Technology Durgapur · INIndian Institute of Science Bangalore · INUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human matrix metalloproteinase (MMP)-1 or collagenase-1 plays a significant role in embryonic development, tissue remodeling, and is also involved in several diseases like arthritis, metastasis, etc. Molecular dynamics simulation studies on hMMP-1 X-ray structures (PDB Id. 1CGE, 1CGF, 1CGL, 1HFC, and 2TCL) suggest that the three conserved water molecules (W

Indexed as

Molecular Dynamics SimulationBinding SitesCationsCrystallography, X-RayHistidineHumansHydrophobic and Hydrophilic InteractionsMatrix Metalloproteinase 1WaterZincCationsHistidineMatrix Metalloproteinase 1MMP1 protein, humanWaterZincMatrix metalloproteinaseMechanismMolecular dynamicsZn ions

Identifiers

PMID28161785
OpenAlexW2584056489

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.