ArticleThrombosis research2017
Hospitalization with infection and incident venous thromboembolism: The ARIC study.
Article in Thrombosis research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Association between the albumin-to-globulin ratio and deep vein thrombosis in older adults receiving home healthcare: a prospective cohort study.Irish journal of medical science · 2026Article
- Development and validation of a prediction model for venous thromboembolic events following hematoma evacuation in patients with spontaneous intracerebral hemorrhage.Neurosurgical review · 2025Article
- Risk of Venous Thromboembolism in Infectious Diseases: A Literature Review.Pathogens (Basel, Switzerland) · 2025Review
- SevereFrontiers in medicine · 2025Article
- Epidemiology and prevention of venous thromboembolism.Nature reviews. Cardiology · 2023Review
- IFITM3 regulates fibrinogen endocytosis and platelet reactivity in nonviral sepsis.The Journal of clinical investigation · 2022Article
- Venous thromboembolism in critically ill patients with pneumonia in the pre-COVID-19 era: Data from a large public database.Research and practice in thrombosis and haemostasis · 2022Article
- Association of COVID-19 With Major Arterial and Venous Thrombotic Diseases: A Population-Wide Cohort Study of 48 Million Adults in England and Wales.Circulation · 2022Article
- Acute infection as a trigger for incident venous thromboembolism: Results from a population-based case-crossover study.Research and practice in thrombosis and haemostasis · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
objectivesAcute triggers for VTE, which may include infection, are understudied, as is the timing and duration of VTE risk after infection. We hypothesized that there is an association between hospitalization with infection and short-term VTE risk that exceeds the known association between hospitalization and VTE.
methodsVTE cases and infections were identified in the Atherosclerosis Risk in Communities (ARIC) cohort. A case-crossover design and conditional logistic regression were used to compare hospitalized infections among VTE cases (14, 30, 42, and 90days before VTE) with corresponding control periods 1year and 2years prior. Since hospitalization is a known VTE trigger, study design and analytical techniques were used to isolate the impact of infection.
resultsThere were 845 adjudicated incident VTE cases. Hospitalization with infection was more common in all case periods compared to equivalent control periods: 14day OR (95% CI)=1.7 (0.5, 5.8), 30day OR (95% CI)=2.7 (1.1, 6.4), 42day OR (95% CI)=2.2 (1.1, 4.7), and 90day OR (95% CI)=1.2 (0.7, 2.0). The association was generally strongest in exposure periods closest to the VTE event and decreased as the time window before VTE increased.
conclusionsThese results support the hypothesis that hospitalized infection is a trigger of VTE. VTE preventive measures may prevent VTE events if used in the peri-infection period but clinical trials are needed.
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