Evidence map›Paper›PMID 28161315›Full record

ReviewSeminars in fetal & neonatal medicine2017

Renal development in the fetus and premature infant.

Stacy Rosenblum, Abhijeet Pal, Kimberly Reidy

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in fetal & neonatal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.

  1. Pooled it
  2. Impact of maternal health on neonatal and long-term kidney outcomes.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  3. Neonatal acute kidney injury and the patent ductus arteriosus.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  4. Review
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  12. Review
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  16. Review
  17. Review
  18. Bilateral renal agenesis: fetal intervention and outcomes.Pediatric nephrology (Berlin, Germany) · 2025
    Review
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Stacy RosenblumDepartment of Pediatrics/Neonatology, Children's Hospital of Montefiore/Einstein, Bronx, NY, USA.
Abhijeet PalDepartment of Pediatrics/Nephrology, Children's Hospital of Montefiore/Einstein, Bronx, NY, USA.
Kimberly ReidyDepartment of Pediatrics/Nephrology, Children's Hospital of Montefiore/Einstein, Bronx, NY, USA. Electronic address: kreidy@montefiore.org.
Children's Hospital at Montefiore · USAlbert Einstein College of Medicine · US

Funding

Role of Par1 Polarity Proteins in Podocyte Development and Glomerular DiseaseK08DK091507 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI REIDY, KIMBERLY JEAN · 2011 to 2015
$667k
Inducible Knockout of Par 1 a/b in the KidneyR03DK105242 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI REIDY, KIMBERLY JEAN · 2015 to 2016
$167k
NIDDK NIH HHS K08 DK091507NIDDK NIH HHS R03 DK105242
6 · The paper itself

Abstract

Congenital abnormalities of the kidney and urinary tract (CAKUT) are one of the leading congenital defects to be identified on prenatal ultrasound. CAKUT represent a broad spectrum of abnormalities, from transient hydronephrosis to severe bilateral renal agenesis. CAKUT are a major contributor to chronic and end stage kidney disease (CKD/ESKD) in children. Prenatal imaging is useful to identify CAKUT, but will not detect all defects. Both genetic abnormalities and the fetal environment contribute to CAKUT. Monogenic gene mutations identified in human CAKUT have advanced our understanding of molecular mechanisms of renal development. Low nephron number and solitary kidneys are associated with increased risk of adult onset CKD and ESKD. Premature and low birth weight infants represent a high risk population for low nephron number. Additional research is needed to identify biomarkers and appropriate follow-up of premature and low birth weight infants into adulthood.

Indexed as

UltrasonographyHumansInfant, PrematureInfant, Premature, DiseasesKidneyKidney DiseasesUltrasonography, PrenatalCongenital abnormalities of the kidney and urinary tract (CAKUT)Fetal ultrasonographyHydronephrosisPrematurityRenal developmentUrinary tract obstruction

Identifiers

PMID28161315
PMCPMC5387761
OpenAlexW2584642371

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.