ReviewJACC. Heart failure2017
Can Vaccinations Improve Heart Failure Outcomes?: Contemporary Data and Future Directions.
Review in JACC. Heart failure, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Updated Cardiovascular Prevention Guideline of the Brazilian Society of Cardiology - 2019.Arquivos brasileiros de cardiologia · 2019Guideline
- The effect of influenza vaccination on mortality and hospitalization in patients with heart failure: a systematic review and meta-analysis.Heart failure reviews · 2019Pooled it
- Article
- Influenza Vaccination Among Patients with Noncommunicable Diseases: A Survey About Awareness, Usage, and Unmet Needs in the Czech Republic.Drugs - real world outcomes · 2025Article
- Current anti-inflammatory strategies for treatment of heart failure: From innate to adaptive immunity.Pharmacological research · 2025Review
- Pneumococcal and Influenza Vaccination Coverage in Patients with Heart Failure: A Systematic Review.Journal of clinical medicine · 2024Review
- Influenza vaccination for elderly, vulnerable and high-risk subjects: a narrative review and expert opinion.Internal and emergency medicine · 2024Review
- Immunizing hearts: exploring the vaccination frontier in heart failure management.Annals of medicine and surgery (2012) · 2024Review
- Article
- The impact of influenza vaccination on cardiovascular diseases.European heart journal supplements : journal of the European Society of Cardiology · 2023Article
- Article
- Vaccine-preventable disease hospitalized patients with heart failure with reduced ejection fraction.Clinical cardiology · 2022Article
- Vaccination for Respiratory Infections in Patients with Heart Failure.Journal of clinical medicine · 2021Review
- Vaccinating Patients with Heart Disease Against COVID-19: The Reasons for Priority.Arquivos brasileiros de cardiologia · 2021Article
- Influenza-associated cardiovascular mortality in older adults in Beijing, China: a population-based time-series study.BMJ open · 2020Article
- Acutely decompensated versus acute heart failure: two different entities.Heart failure reviews · 2020Review
- Predictors of infection-related rehospitalization in heart failure patients and its impact on long-term survival.Journal of cardiovascular medicine (Hagerstown, Md.) · 2020Observational
- Innovation in Ambulatory Care of Heart Failure in the Era of Coronavirus Disease 2019.Heart failure clinics · 2020Review
- The pharmacist and pharmacy have evolved to become more than the corner drugstore: a win for vaccinations and public health.Human vaccines & immunotherapeutics · 2020Article
- Clinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes?Cardiac failure review · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Heart failure (HF) is a chronic syndrome characterized by acute exacerbations. There is significant overlap between respiratory infections and exacerbation of underlying HF. Vaccination against respiratory infections in patients with HF could serve as a potential cost-effective intervention to improve patients' quality of life and clinical outcomes. The benefits of influenza vaccination in secondary prevention of ischemic heart disease have been previously studied. However, the evidence for influenza and pneumococcal vaccination specifically in the HF population is less well established. Furthermore, questions around the optimal timing, dose, frequency, and implementation strategies are largely unanswered. This review highlights the current evidence for vaccination against influenza and pneumococcal pneumonia in HF and cardiovascular disease. It summarizes current understanding of the pathophysiologic mechanisms in which vaccination may provide cardioprotection. Finally, it offers opportunities for further investigation on the effects of vaccination in the HF population, spanning basic science, translational research, and large clinical trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.