Evidence map›Paper›PMID 28160524›Full record

ArticleJournal of veterinary internal medicine2017

Urinary F

W Whitehouse, J Quimby, S Wan, K Monaghan, R Robbins, L A Trepanier

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Plasma and urinary FJournal of feline medicine and surgery · 2021
    Article
  10. Isoprostanes in Veterinary Medicine: Beyond a Biomarker.Antioxidants (Basel, Switzerland) · 2021
    Review
  11. Feline urinary FJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020
    Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

W WhitehouseDepartment of Medical Sciences, University of Wisconsin-Madison, Madison, WI.
J QuimbyCollege of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO.
S WanDepartment of Medical Sciences, University of Wisconsin-Madison, Madison, WI.
K MonaghanDepartment of Medical Sciences, University of Wisconsin-Madison, Madison, WI.
R RobbinsDepartment of Medical Sciences, University of Wisconsin-Madison, Madison, WI.
L A TrepanierDepartment of Medical Sciences, University of Wisconsin-Madison, Madison, WI.
University of Wisconsin–Madison · USColorado State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundF

objectivesTo determine whether cats with advancing CKD have increasing urinary F ANIMALS: Control cats without evidence of CKD (≥6 years old; n = 11), and cats with IRIS stage 1 (n = 8), 2 (n = 38), 3 (n = 21), and 4 (n = 10) CKD.

methodsThis was a prospective observational study. Urinary F

resultsUrinary IsoPs were increased, but not significantly, in cats with stage 1 CKD (median 263 pg/mg creatinine; range, 211-380) compared to controls (182 pg/mg; range, 80-348) and decreased significantly from stage 1 through advancing CKD (stage 2, 144 pg/mg; range, 49-608; stage 3, 102 pg/mg; range, 25-158; stage 4, 67 pg/mg; range, 26-117; P < .01). Urinary IsoPs were inversely correlated with serum creatinine (r = -0.66, P < .0001). CONCLUSION AND CLINICAL IMPORTANCE: Urinary IsoPs are significantly higher in early CKD (stage 1) compared to cats with more advanced CKD. Additional studies are warranted to characterize oxidative stress in cats with stage 1 CKD and determine whether early antioxidant treatments have a protective effect on CKD progression.

Indexed as

AnimalsBiomarkersCat DiseasesCatsCreatinineF2-IsoprostanesFemaleHypertensionMaleOxidative StressProspective StudiesProteinuriaRenal Insufficiency, ChronicBiomarkersCreatinineF2-IsoprostanesBiomarkerFelineOxidative stressProstanoidsRedoxRenal failure

Identifiers

PMID28160524
PMCPMC5354001
OpenAlexW2585720624

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.