ArticleDocumenta ophthalmologica. Advances in ophthalmology2017
Constant luminance (cd·s/m
Article in Documenta ophthalmologica. Advances in ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02466607 (Study of Stimulus Parameters in Flicker Electroretinogram), which is not on this map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Study of Stimulus Parameters in Flicker Electroretinogram (ERG)
Who cites it
16 citing papers in PubMed.
- The reproducibility of handheld ERGs recorded with skin electrode and natural pupils.Documenta ophthalmologica. Advances in ophthalmology · 2025Article
- A study on electroretinography as a biomarker for seasonal vulnerability in depression.Translational psychiatry · 2025Article
- Synthetic electroretinogram signal generation using a conditional generative adversarial network.Documenta ophthalmologica. Advances in ophthalmology · 2025Article
- Light-adapted electroretinograms of eyes with cataract recorded using the HE-2000 system before and after mydriasis.Scientific reports · 2025Article
- Minimizing Pupil Size Dependence in Flicker ERG Using Stiles-Crawford Compensation.Translational vision science & technology · 2025Article
- The electroretinography to identify biomarkers of idiopathic hypersomnia and narcolepsy type 1.Journal of sleep research · 2025Article
- Investigating the Structural and Functional Changes in the Optic Nerve in Patients with Early Glaucoma Using the Optical Coherence Tomography (OCT) and RETeval System.Sensors (Basel, Switzerland) · 2023Article
- Comparing the RETevalDocumenta ophthalmologica. Advances in ophthalmology · 2023Article
- Flicker electroretinogram in newborn infants.Documenta ophthalmologica. Advances in ophthalmology · 2022Article
- Large-conductance calcium-activated potassium channel haploinsufficiency leads to sensory deficits in the visual system: a case report.Journal of medical case reports · 2022Article
- Mydriasis-Free Flicker Electroretinograms in 204 Healthy Children Aged 0-18 Years: Reference Data From Two Cohorts.Translational vision science & technology · 2021Article
- Electroretinography and contrast sensitivity, complementary translational biomarkers of sensory deficits in the visual system of individuals with fragile X syndrome.Journal of neurodevelopmental disorders · 2021Article
- Artificial iris performance for smart contact lens vision correction applications.Scientific reports · 2020Article
- Enhancing Risk Assessment in Patients with Diabetic Retinopathy by Combining Measures of Retinal Function and Structure.Translational vision science & technology · 2020Article
- Absence of Excess Intra-Individual Variability in Retinal Function in People With Schizophrenia.Frontiers in psychiatry · 2020Article
- Hand-held, dilation-free, electroretinography in children under 3 years of age treated with vigabatrin.Documenta ophthalmologica. Advances in ophthalmology · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare the effect of variable pupil size on the flicker electroretinogram (ERG) between a stimulus having constant luminance and a stimulus having constant retinal illuminance (constant Troland) that compensates for pupil size.
methodsSubjects (n = 18) were tested with 12 pairs of the stimuli. The stimulus pair consisted of the ISCEV standard constant luminance stimulus (3 cd·s/m
resultsWith natural pupils, intra-subject variability was lower with the constant Troland stimulus, while inter-subject variability was similar between stimuli. During pupil dilation, the constant Troland stimulus did not have a dependence on pupil size up to 6.3 mm and had slightly larger amplitudes with longer implicit times for fully dilated pupils. For the constant luminance stimulus, waveform amplitudes varied by 22% per mm change in pupil diameter, or by 48% over the 2.2 mm diameter range measured in dilated pupil size. There was no difference in inter-subject variability between constant Troland natural pupils and the same subjects with a constant luminance stimulus when dilated (i.e., the ISCEV standard condition).
conclusionsThese results suggest that a constant Troland flicker ERG test with natural pupils may be advantageous in clinical testing. Because of its insensitivity to pupil size, constant Troland stimuli should produce smaller reference ranges, which in turn should improve the sensitivity for detection of abnormalities and for monitoring changes. In addition, the test can be administered more efficiently as it does not require artificial dilation. CLINICAL TRIAL REGISTRATION NUMBER: This trial is registered at ClinicalTrials.gov (NCT02466607).
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