ArticleBiogerontology2017
Multidimensional predictors of physical frailty in older people: identifying how and for whom they exert their effects.
Article in Biogerontology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 97 citations in OpenAlex.
- The conceptualisation and measurement of social frailty in older people: an umbrella review.The Journal of frailty & aging · 2025Pooled it
- Allostatic Load Measurement: A Systematic Review of Reviews, Database Inventory, and Considerations for Neighborhood Research.International journal of environmental research and public health · 2022Pooled it
- Relationship among frailty, nutrition, depression and quality of life in the older population.BMC geriatrics · 2026Article
- Regional and Socioeconomic Disparities in Frailty Across Tasmania: Evidence From Island Study Linking Ageing and Neurodegenerative Disease.Australasian journal on ageing · 2026Article
- Article
- Abnormal Blood Biomarkers and Cumulative Disability Burden in Middle-Aged and Older Adults: Evidence from Two Nationally Representative Surveys in the United States and China.Journal of cardiovascular development and disease · 2025Article
- Prevalence of frailty and associated factors in Shanghai older community-dwelling adults: a cross-sectional study.BMJ open · 2025Article
- Does Allostatic Load in 50-89-Year-Olds Predict the Development of Frailty? Evidence From a National Longitudinal Study Over 12 Years.Stress and health : journal of the International Society for the Investigation of Stress · 2025Article
- Allostatic load and its determinants in a German sample-Results from the Carla cohort.PloS one · 2025Article
- Predicting Multiple Outcomes Associated with Frailty based on Imbalanced Multi-label Classification.Journal of healthcare informatics research · 2024Article
- Identification and prediction of frailty among community-dwelling older Japanese adults based on Bayesian network analysis: a cross-sectional and longitudinal study.BMC public health · 2024Article
- Reproductive factors and their association with physical and comprehensive frailty in middle-aged and older women: a large-scale population-based study.Human reproduction open · 2024Article
- Social isolation and depression as risk factors for weight loss of 5kg or more among older Korean adults.PloS one · 2024Article
- Inclusion body myositis-health-related quality of life and care situation during phases of the "patience journey" in Germany: results from a qualitative study.Health and quality of life outcomes · 2023Article
- Palliative Care Needs of Physically Frail Community-Dwelling Older Adults With Heart Failure.Journal of pain and symptom management · 2023Article
- Midlife Life's Simple 7, Psychosocial Health, and Physical Frailty, Hospital Frailty, and Comprehensive Frailty 10 Years Later.Nutrients · 2023Article
- Article
- Dietary Quality, Sleep Quality and Muscle Mass Predicted Frailty among Chinese Postmenopausal Women in Malaysia.International journal of environmental research and public health · 2022Article
- Assessing the psychosocial dimensions of frailty among older adults in Singapore: a community-based cross-sectional study.BMJ open · 2022Article
- Perceived Social Support and Associated Factors Among Community-Dwelling Older Adults With Frailty and Pre-frailty in Hangzhou, China.Frontiers in psychiatry · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Physical frailty in older people is an escalating health and social challenge. We investigate its physical, psychological, and social predictors, including how and for whom these conditions exert their effects. For 4638 respondents aged 65-89 years from wave 2 of the English Longitudinal Study of Ageing, we examine prediction of future physical frailty by physical, psychological, and social conditions using latent growth curve analysis with multiple indicators. In addition, we explore their indirect effects through disease and physiologic decline, and repeat these analyses after stratification by gender, age group, and selected conditions which are possible moderators. We find that chronic disease, allostatic load, low physical activity, depressive symptoms, cognitive impairment, and poor social support all predict future physical frailty. Furthermore, chronic disease and allostatic load mediate the effects of low physical activity, depressive symptoms, and cognitive impairment on future physical frailty. Finally, although poor social integration is not a predictor of future physical frailty, this condition moderates the indirect effect of poor social support through chronic disease by rendering it stronger. By virtue of their roles as predictor, mediator, or moderator on pathways to physical frailty, chronic disease, allostatic load, low physical activity, cognitive impairment, depressive symptoms, poor social support, and poor social integration are potentially modifiable target conditions for population-level health and social interventions to reduce future physical frailty in older people.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.