ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2017
Descemet membrane endothelial keratoplasty for graft failure following penetrating keratoplasty.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 47 citations in OpenAlex.
- Anterior segment optical coherence tomography (AS-OCT) assisted analysis of characteristics of graft dehiscence after Descemet membrane endothelial keratoplasty (DMEK) for failed penetrating keratoplasty.Acta ophthalmologica · 2025Article
- Descemet Membrane Endothelial Keratoplasty for Penetrating Keratoplasty.Journal of pharmacy & bioallied sciences · 2024Article
- Descemet Membrane Endothelial Keratoplasty after failed penetrating keratoplasty- case series and review of the literature.BMC ophthalmology · 2024Review
- Graft rejection in component keratoplasty.Indian journal of ophthalmology · 2023Review
- Graft failure rate and complications after Descemet membrane endothelial keratoplasty in eyes with pre-existing glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Observational
- Descemet's membrane endothelial keratoplasty for primary graft failure after penetrating keratoplasty.Arquivos brasileiros de oftalmologia · 2022Article
- DMEK after penetrating keratoplasty: cohort with DMEK grafts and descemetorhexis larger than full-thickness graft.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
- Evolving Techniques and Indications of Descemet Membrane Endothelial Keratoplasty.Turkish journal of ophthalmology · 2021Review
- [Descemet membrane endothelial keratoplasty (DMEK) for graft failure after penetrating keratoplasty and in vascularized high-risk eyes].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2021Review
- The Human Tissue-Engineered Cornea (hTEC): Recent Progress.International journal of molecular sciences · 2021Review
- [Descemet membrane endothelial keratoplasty DMEK - Donor and recipient step by step].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020Review
- Double decker endothelial keratoplasty.Indian journal of ophthalmology · 2019Article
- Automated segmentation of the corneal endothelium in a large set of 'real-world' specular microscopy images using the U-Net architecture.Scientific reports · 2019Article
- Differential Survival of Penetrating and Lamellar Transplants in Management of Failed Corneal Grafts.JAMA ophthalmology · 2018Article
- Risk Factors for Endothelial Decompensation after Penetrating Keratoplasty and Its Novel Therapeutic Strategies.Journal of ophthalmology · 2018Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDescemet membrane endothelial keratoplasty (DMEK) is superior to penetrating keratoplasty (PK) in terms of visual rehabilitation, intraoperative safety and risk of rejection. Therefore, it seems reasonable to perform DMEK in eyes with endothelial failure following PK. We herein report our first clinical results.
methodsNineteen eyes with endothelial graft failure following PK were treated with DMEK. The majority of these eyes (12) had limited visual potential. The major indication for DMEK was pain relief in patients with bullous keratopathy. Visual acuity (VA), central corneal thickness (CCT), rate of graft dislocations, graft survival, graft rejections and other complications were extracted from the medical records.
resultsAlthough comorbidities limiting VA were present in 12 of the 19 eyes, VA increased from 0.05 to 0.1 (median) in 16 eyes. CCT decreased substantially (range 63-363 μm). Rebubbling was necessary in five eyes with incomplete graft adherence. There were two immunologic graft reactions and three graft failures. No major complications like endophthalmitis or expulsive bleeding occurred.
conclusionsDMEK is feasible to treat endothelial graft failure following PK. This is even true for eyes with limited visual potential.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.