SynthesisBMJ open2017
Effects of pulmonary rehabilitation in lung transplant candidates: a systematic review.
Synthesis in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07660991 (Pulmoner Rehabilitasyon Alan akciğer Nakil adaylarında hidroksimetilbütirat Takviyesinin değerlendirilmesi), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pulmoner Rehabilitasyon Alan akciğer Nakil adaylarında hidroksimetilbütirat Takviyesinin değerlendirilmesi
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pulmonary Rehabilitation for Adults with Chronic Respiratory Disease: An Official American Thoracic Society Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2023Guideline
- Exercise training for lung transplant candidates and recipients: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2020Pooled it
- CT-derived skeletal muscle predicts lung transplant approval.JHLT open · 2026Article
- Article
- From Living Room to Operating Room for Patients with Pulmonary Surgeries: A Systematic Review of Literature.Journal of clinical medicine · 2025Review
- The history of pulmonary rehabilitation: learning from the past to shape a brighter future.Breathe (Sheffield, England) · 2025Review
- Rehabilitation for Physical Frailty in Lung Transplant Candidates: A Systematic Review.Cardiopulmonary physical therapy journal · 2025Article
- Lung transplantation for pulmonary chronic graft-versus-host disease: a missed opportunity?JHLT open · 2025Review
- Characterizing adult rehabilitation programs for solid organ transplant candidates and recipients across Canada.Frontiers in rehabilitation sciences · 2025Article
- Influence of acute kidney injury and its recovery subtypes on patient-centered outcomes after lung transplantation.Scientific reports · 2024Article
- Rehabilitation interventions to modify physical frailty in adults before lung transplantation: a systematic review protocol.BMJ open · 2024Article
- Group Versus Individual Rehabilitation in Lung Transplantation: A Retrospective Noninferiority Assessment.Cardiopulmonary physical therapy journal · 2024Article
- Extending the Benefits of Pulmonary Rehabilitation to New Groups: Reply to AnidiAmerican journal of respiratory and critical care medicine · 2023Article
- Multimodal Prehabilitation in Heart Transplant Recipients Improves Short-Term Post-Transplant Outcomes without Increasing Costs.Journal of clinical medicine · 2023Article
- Antifibrotic therapy in idiopathic pulmonary fibrosis candidates for lung transplantation undergoing pulmonary rehabilitation.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023Observational
- The Intersection of Aging and Lung Transplantation: its Impact on Transplant Evaluation, Outcomes, and Clinical Care.Current transplantation reports · 2022Article
- The effect of early tracheal extubation combined with physical training on pulmonary rehabilitation of patients after lung transplantation: a randomized controlled trial.Journal of thoracic disease · 2022Article
- Anesthetic considerations in lung transplantation: past, present and future.Journal of thoracic disease · 2021Review
- Respiratory Sarcopenia and Sarcopenic Respiratory Disability: Concepts, Diagnosis, and Treatment.The journal of nutrition, health & aging · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this systematic review of randomised controlled trials (RCTs), and quasi-experimental and retrospective studies is to investigate the effects of pulmonary rehabilitation (PR) in patients with advanced chronic disease on the waiting list for lung transplantation.
settingPR performed for inpatient or outpatient lung transplant candidates.
interventionPR programme including aerobic exercise training and/or resistance exercise training. PRIMARY AND SECONDARY OUTCOMES: Quality of life and exercise capacity (primary outcomes). Survival rate after transplant surgery; pulmonary function; respiratory muscle strength; psychological aspects; upper and lower extremity muscle strength and adverse effects (secondary outcomes). Two review authors independently selected the studies, assessed study quality and extracted data. Studies in any language were included.
resultsThis was a systematic review and studies were searched on the Cochrane Library, MEDLINE, EMBASE, CINAHL and PEDro. Experimental and retrospective studies evaluating the effects of PR in candidates for lung transplantation (>18 years old) with any lung diseases were included. 2 RCTs, and two quasi-experimental and two retrospectives studies, involving 1305 participants were included in the review. 5 studies included an enhancement reported in quality of life using the Short Form 36 questionnaire and showed improvements in some domains. All studies included exercise capacity evaluated through 6 min walk test and in five of them, there were improvements in this outcome after PR. Owing to the different characteristics of the studies, it was not possible to perform a meta-analysis.
conclusionsStudies included in this review showed that PR is an effective treatment option for patients on the waiting list for lung transplantation and can improve quality of life and exercise capacity in those patients. Although individual studies reported positive effects of PR, this review shows that there is a need for more studies of a high methodological quality addressing PR effects in lung transplant candidates. TRIAL REGISTRATION NUMBER: PROSPERO CDR42015025110.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.