Evidence map›Paper›PMID 28159812›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2017

Right ventricular metabolism during venoarterial extracorporeal membrane oxygenation in immature swine heart in vivo.

Masaki Kajimoto, Dolena R Ledee, Nancy G Isern, Michael A Portman

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Statistical considerations in reporting cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2018
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Masaki KajimotoCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington.
Dolena R LedeeCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington.
Nancy G IsernEnvironmental Molecular Sciences Laboratory, Pacific Northwest National Laboratories, Richland, Washington; and.
Michael A PortmanCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington; michael.portman@seattlechildrens.org.
Environmental Molecular Sciences Laboratory · USUniversity of Washington · US

Funding

Phase 3 Triiodothyronine Supplementation for Infants After Cardiopulmonary BypassR01FD004362 · FDA · SEATTLE CHILDREN'S HOSPITAL · PI PORTMAN, MICHAEL A · 2014 to 2017
$1.6M
Regulation Mechanisms of Thyroid Hormone Receptors in the HeartK01HL120886 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI LEDEE, DOLENA ROSELLE · 2014 to 2018
$723k
FDA HHS R01 FD004362NHLBI NIH HHS K01 HL120886
6 · The paper itself

Abstract

Venoarterial extracorporeal membrane oxygenation (VA-ECMO) provides hemodynamic rescue for patients encountering right or left ventricular (RV or LV) decompensation, particularly after surgery for congenital heart defects. ECMO, supported metabolically by parenteral nutrition, provides reductions in myocardial work and energy demand and, therefore, enhances functional recovery. The RV must often assume systemic ventricular pressures and function on weaning from VA-ECMO. However the substrate utilization responses of the RV to VA-ECMO or stimulation are unknown. We determined RV and LV substrate utilization response to VA-ECMO in immature swine heart. Mixed-breed male Yorkshire pigs (33-49 days old) underwent normal pressure volume loading (control,

Indexed as

Extracorporeal Membrane OxygenationAdenosine TriphosphateAnimalsEnergy MetabolismFatty AcidsHeartHeart VentriclesHemodynamicsLactic AcidMagnetic Resonance SpectroscopyMaleMyocardiumNADPhosphocreatinePyruvate Dehydrogenase ComplexSwineAdenosine TriphosphateFatty AcidsLactic AcidNADPhosphocreatinePyruvate Dehydrogenase ComplexTriiodothyroninecardiac metabolismextracorporeal circulationpediatricsthyroid hormone

Identifiers

PMID28159812
PMCPMC5407156
OpenAlexW2584993554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.