Evidence map›Paper›PMID 28159804›Full record

ArticleRNA (New York, N.Y.)2017

Lariat capping as a tool to manipulate the 5' end of individual yeast mRNA species in vivo.

Nicolai Krogh, Max Pietschmann, Manfred Schmid, Torben Heick Jensen, Henrik Nielsen

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nicolai KroghDepartment of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Max PietschmannDepartment of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Manfred SchmidDepartment of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark.
Torben Heick JensenDepartment of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark.
Henrik NielsenDepartment of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
University of Copenhagen · DKAarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 5' cap structure of eukaryotic mRNA is critical for its processing, transport, translation, and stability. The many functions of the cap and the fact that most, if not all, mRNA carries the same type of cap makes it difficult to analyze cap function in vivo at individual steps of gene expression. We have used the lariat capping ribozyme (LCrz) from the myxomycete

Indexed as

Cell NucleusGreen Fluorescent ProteinsHalf-LifeProtein BiosynthesisRNA Cap AnalogsRNA, CatalyticRNA, MessengerRNA TransportSaccharomyces cerevisiae7-methylguanosine triphosphateGreen Fluorescent ProteinsRNA Cap AnalogsRNA, CatalyticRNA, Messengerlariat capping ribozymem7GmRNA processingmRNA turnoverpolyadenylation

Identifiers

PMID28159804
PMCPMC5393178
OpenAlexW2583663480

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.